Pretreatment neutrophil-to-lymphocyte ratio was a predictor of lymph node metastasis in endometrial cancer patients

T Aoyama, M Takano, M Miyamoto, T Yoshikawa… - Oncology, 2019 - karger.com
Objective: The pretreatment neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte
ratio (PLR) have been reported to be useful as markers for prognostic factors and …

[HTML][HTML] JAK2/STAT3 pathway as a therapeutic target in ovarian cancers

T Yoshikawa, M Miyamoto, T Aoyama… - Oncology …, 2018 - spandidos-publications.com
The activation of JAK2/STAT3 pathway has been reported to have critical roles in several
solid tumors. The present study aimed to evaluate the correlation between JAK2/STAT3 …

Clinical significance of UDP-glucuronosyltransferase 1A1* 6 for toxicities of combination chemotherapy with irinotecan and cisplatin in gynecologic cancers: a …

M Takano, M Kato, T Yoshikawa, N Sasaki, J Hirata… - Oncology, 2009 - karger.com
Background: To investigate the effects of UDP-glucuronosyltransferase 1A1 (UGT1A1) *28, *6
and *27 in patients with gynecologic cancer who received chemotherapy with irinotecan …

[HTML][HTML] On-tissue polysulfide visualization by surface-enhanced Raman spectroscopy benefits patients with ovarian cancer to predict post-operative chemosensitivity

…, A Kubo, M Itoh, WY Chen, M Takano, T Yoshikawa… - Redox Biology, 2021 - Elsevier
Chemosensitivity to cisplatin derivatives varies among individual patients with intractable
malignancies including ovarian cancer, while how to unlock the resistance remain unknown. …

Psoas muscle volume as a predictor of peripheral neurotoxicity induced by primary chemotherapy in ovarian cancers

T Yoshikawa, M Takano, M Miyamoto, I Yajima… - Cancer Chemotherapy …, 2017 - Springer
Purpose Low skeletal muscle mass (sarcopenia) has been reported to have an influence on
survival and toxicities of chemotherapy in several solid tumors. The impact of sarcopenia on …

Clear cell adenocarcinoma associated with clear cell adenofibromatous components: a subgroup of ovarian clear cell adenocarcinoma with distinct clinicopathologic …

S Yamamoto, H Tsuda, T Yoshikawa… - The American journal …, 2007 - journals.lww.com
We occasionally encountered clear cell adenofibromatous (CCAF) components coexisting
in the ovarian clear cell adenocarcinoma (CCA). To reveal the clinicopathologic significance …

[HTML][HTML] Psoas muscle index at the fifth lumbar vertebra as a predictor of survival in epithelial ovarian cancers

T Yoshikawa, M Miyamoto… - Molecular and …, 2021 - spandidos-publications.com
Almost a quarter of a century has passed since the term sarcopenia was defined. Sarcopenia
is recognized as a poor prognostic factor in a variety of cancer types. In ovarian cancer, it …

Phenoxodiol increases cisplatin sensitivity in ovarian clear cancer cells through XIAP down-regulation and autophagy inhibition

…, H Matuura, T Sakamoto, T Yoshikawa… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: To investigate whether XIAP down-regulation and autophagy inhibition
sensitize ovarian clear cell cancer cells to cisplatin. Materials and Methods: The ovarian clear …

[HTML][HTML] Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas

…, T Aoyama, H Soyama, T Yoshikawa… - Journal of …, 2017 - ncbi.nlm.nih.gov
Objective Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor
prognosis due to chemoresistance. The association of autophagy-related proteins and …

A pathological study using 2014 WHO criteria reveals poor prognosis of grade 3 ovarian endometrioid carcinomas

…, M Kuwahara, H Ishibashi, H Matuura, T Yoshikawa… - in vivo, 2018 - iv.iiarjournals.org
Background/Aim: The purpose of this study was to compare the clinical behavior of several
grades of endometrioid carcinoma (EC) compared to high-grade serous carcinoma (HGSC), …