Epidemiology of venous thromboembolism in 9489 patients with malignant glioma

TJ Semrad, R O'Donnell, T Wun, H Chew… - Journal of …, 2007 - thejns.org
Object The authors sought to define the incidence of symptomatic venous thromboembolism
(VTE) in patients harboring malignant gliomas. Methods The authors conducted a …

Immunotherapy and targeted therapy for advanced gastroesophageal cancer: ASCO guideline

…, H Park, A Saeed, TJ Semrad… - Journal of Clinical …, 2023 - ingentaconnect.com
PURPOSE To develop recommendations involving targeted therapies for patients with
advanced gastroesophageal cancer. METHODS The American Society of Clinical Oncology …

Randomized trial of irinotecan and cetuximab with or without vemurafenib in BRAF-mutant metastatic colorectal cancer (SWOG 1406).

…, SE Wang, CH Lieu, SG Eckhardt, TJ Semrad… - 2017 - ascopubs.org
520 Background: BRAF V600 mutations are associated with rare objective responses to the
mutated BRAF inhibitor vemurafenib in patients with mCRC. Blockade of BRAF V600 by …

Cetuximab plus carboplatin and paclitaxel with or without bevacizumab versus carboplatin and paclitaxel with or without bevacizumab in advanced NSCLC (SWOG …

RS Herbst, MW Redman, ES Kim, TJ Semrad… - The Lancet …, 2018 - thelancet.com
Background EGFR antibodies have shown promise in patients with advanced non-small-cell
lung cancer (NSCLC), particularly with squamous cell histology. We hypothesised that …

Phase I trial of arginine deprivation therapy with ADI-PEG 20 plus docetaxel in patients with advanced malignant solid tumors

…, T Li, MP Dutia, K Kelly, IY Gong, T Semrad… - Clinical Cancer …, 2015 - AACR
Purpose: This phase I study examined the toxicity and tolerability of pegylated arginine
deiminase (ADI-PEG 20) in combination with docetaxel in patients with advanced solid …

Role of treatment deintensification in the management of p16+ oropharyngeal cancer: ASCO provisional clinical opinion

…, CU Jones, M Kaufman, QT Le, TJ Semrad… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE An ASCO provisional clinical opinion offers timely clinical direction to ASCO’s
membership after publication or presentation of potentially practice-changing data from major …

Fibroblast growth factor signaling in non–small-cell lung cancer

TJ Semrad, PC Mack - Clinical lung cancer, 2012 - Elsevier
Despite recent progress in the treatment on non–small cell lung cancer (NSCLC), outcomes
remain suboptimal. Treatment advances that target the epidermal growth factor receptor (…

Geographic variation of racial/ethnic disparities in colorectal cancer testing among Medicare enrollees

TJ Semrad, DJ Tancredi, LM Baldwin, P Green… - Cancer, 2011 - Wiley Online Library
BACKGROUND: The Medicare population has documented racial/ethnic disparities in
colorectal cancer (CRC) screening, but it is unknown whether these disparities differ across …

A phase II study of bevacizumab and temsirolimus in advanced extra-pancreatic neuroendocrine tumors

…, J Strosberg, TJ Hobday, T Semrad… - Endocrine-related …, 2023 - erc.bioscientifica.com
We assessed the efficacy and safety of combining bevacizumab with temsirolimus in patients
with advanced extra-pancreatic neuroendocrine tumors. This NCI-sponsored multicenter, …

Oxaliplatin–DNA adducts as predictive biomarkers of FOLFOX response in colorectal cancer: A potential treatment optimization strategy

M Zimmermann, T Li, TJ Semrad, CY Wu, A Yu… - Molecular cancer …, 2020 - AACR
FOLFOX is one of the most effective treatments for advanced colorectal cancer. However,
cumulative oxaliplatin neurotoxicity often results in halting the therapy. Oxaliplatin functions …