Background DC derived-exosomes are nanomeric vesicles harboring functional MHC/peptide
complexes capable of promoting T cell immune responses and tumor rejection. Here we …

BACKGROUND The clinicopathologic features of infiltrating lobular carcinoma (ILC), which
represents 5% to 15% of all breast cancers, are still controversial. In particular, the high …

Purpose Active immunization against the tumor-specific MAGE-A3 antigen is followed by a
few but impressive and durable clinical responses. This randomized phase II trial evaluated …

Purpose To evaluate the toxicity, antitumoral effectiveness, and immunogenicity of repeated
vaccinations with ALVAC miniMAGE-1/3, a recombinant canarypox virus containing a …

The purpose of this phase 1/2 study was to evaluate toxicity, tumor evolution and immunologic
response following administration of a fixed dose of a recombinant MAGE‐3 protein by …

Specific HPV DNA sequences are associated with more than 90% of invasive carcinomas of
the uterine cervix. Viral E6 and E7 oncogenes are key mediators in cell transformation by …

Vaccination of melanoma patients with tumor-specific antigens recognized by cytolytic T
lymphocytes (CTL) produces significant tumor regressions in a minority of patients. These …

PURPOSE Ocular melanoma is characterized by a high rate of liver metastases and is
associated with a median survival time less than 5 months. There is no standard treatment …

PURPOSE In patients with stage IV melanoma, durable responses have been reported with
treatment regimens that involve high-dose interleukin-2 (IL-2). We analyze long-term results …

BACKGROUND This retrospective study evaluates the results of a regimen of high‐dose
intrathecal methotrexate and the prognostic factors for response in patients with meningeal …