Phase III study of docetaxel compared with vinorelbine in elderly patients with advanced non–small-cell lung cancer: Results of the West Japan Thoracic Oncology …

…, M Takada, N Katakami, K Matsui, T Shinkai… - Journal of Clinical …, 2006 - ascopubs.org
Purpose Docetaxel has shown activity in elderly patients with advanced non–small-cell lung
cancer (NSCLC). This randomized phase III trial evaluated the efficacy and safety of …

Phase III study, V-15-32, of gefitinib versus docetaxel in previously treated Japanese patients with non–small-cell lung cancer

…, M Tsuboi, K Nakagawa, T Shinkai… - Journal of Clinical …, 2008 - ascopubs.org
Purpose This phase III study (V-15-32) compared gefitinib (250 mg/d) with docetaxel (60 mg/m
2 ) in patients (N = 489) with advanced/metastatic non–small-cell lung cancer (NSCLC) …

The incidence of secondary tumors of the heart and pericardium: a 10-year study

K Mukai, T Shinkai, K Tominaga… - Japanese journal of …, 1988 - academic.oup.com
Secondary tumors of the heart and pericardium are much more common than primary
tumors. During a 10-year period (1976–1985), only one instance of a primary tumor (malignant …

[HTML][HTML] Randomized phase II study of first-line carboplatin-paclitaxel with or without bevacizumab in Japanese patients with advanced non-squamous non-small-cell …

…, T Hida, N Yamamoto, M Kawahara, T Shinkai… - Lung cancer, 2012 - Elsevier
PURPOSE: This multicenter, randomized, open-label, phase II study (JO19907) compared
the efficacy and safety of first-line carboplatin-paclitaxel (CP) alone with bevacizumab-CP in …

Etoposide and cisplatin versus irinotecan and cisplatin in patients with limited-stage small-cell lung cancer treated with etoposide and cisplatin plus concurrent …

…, M Harada, H Okamoto, N Yamamoto, T Shinkai… - The Lancet …, 2014 - thelancet.com
Background Four cycles of etoposide plus cisplatin and accelerated hyperfractionated
thoracic radiotherapy (AHTRT) is the standard of care for limited-stage small-cell lung cancer (…

[HTML][HTML] A phase I dose-escalation study of ZD6474 in Japanese patients with solid, malignant tumors

…, H Murakami, A Horiike, Y Fujisaka, T Shinkai… - Journal of Thoracic …, 2006 - Elsevier
Introduction ZD6474 (vandetanib) is an orally available inhibitor of vascular endothelial
growth factor receptor, epidermal growth factor receptor, and RET receptor tyrosine kinase …

Pharmacokinetics of (glycolato-0, 0′)-diammine platinum (II), a new platinum derivative, in comparison with cisplatin and carboplatin

Y Sasaki, T Tamura, K Eguchi, T Shinkai… - Cancer chemotherapy …, 1989 - Springer
The pharmacokinetics of (glycolato-0,0′)-diammine platinum (II) (254-S; NSC 375101D),
one of the new platinum analogues, was examined in a phase I study of this drug and …

Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with …

…, M Saito, S Miura, K Eguchi, T Shinkai… - Breast cancer research …, 2010 - Springer
We evaluated the efficacy and safety of sequential therapy with trastuzumab monotherapy (H-mono)
followed by H plus docetaxel (D) after disease progression (H → H + D) versus …

Serum levels of cytokines in patients with untreated primary lung cancer.

…, Y Ohe, F Oshita, T Tamura, T Shinkai… - Clinical cancer research …, 1996 - AACR
To evaluate the relationships between serum endogenous cytokine levels and their clinical
implications in cancer patients, we measured the serum levels of endogenous granulocyte …

Intradural parenchymal involvement in the spinal subarachnoid space associated with primary lung cancer

H Okamoto, T Shinkai, Y Matsuno, N Saijo - Cancer, 1993 - Wiley Online Library
Background. Intradural parenchymal involvement (IPI) in the spinal subarachnoid space
associated with primary lung cancer is rare. A retrospective study was undertaken to investigate …