Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer …

…, T Koichiro, W Junichiro, Y Naohito, Y Yutaka, Y Teruo… - The Lancet, 2020 - thelancet.com
Background Pembrolizumab monotherapy showed durable antitumour activity and manageable
safety in patients with metastatic triple-negative breast cancer. We aimed to examine …

Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis

T Yamauchi, J Yamauchi, T Kuwata… - Proceedings of the …, 2000 - National Acad Sciences
PCAF plays a role in transcriptional activation, cell-cycle arrest, and cell differentiation in
cultured cells. PCAF contributes to transcriptional activation by acetylating chromatin and …

Vitamin E δ-tocotrienol augments the antitumor activity of gemcitabine and suppresses constitutive NF-κB activation in pancreatic cancer

K Husain, RA Francois, T Yamauchi, M Perez… - Molecular cancer …, 2011 - AACR
The NF-κB transcription factor functions as a crucial regulator of cell survival and
chemoresistance in pancreatic cancer. Recent studies suggest that tocotrienols, which are the …

Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage

S Kharbanda, P Pandey, T Yamauchi… - … and cellular biology, 2000 - Taylor & Francis
The c-Abl protein tyrosine kinase is activated by certain DNA-damaging agents and regulates
induction of the stress-activated c-Jun N-terminal protein kinase (SAPK). Here we show …

Potential role of pNF-H, a biomarker of axonal damage in the central nervous system, as a predictive marker of chemotherapy-induced cognitive impairment

…, M Sumitani, T Kogure, T Yamauchi, H Yamauchi - Clinical Cancer …, 2015 - AACR
Purpose: Chemotherapy-induced cognitive impairment (CICI) is a clinically significant problem.
Previous studies using magnetic resonance imaging indicated structural changes in the …

Dupilumab treatment ameliorates clinical and hematological symptoms, including blood eosinophilia, in patients with atopic dermatitis

T Yamauchi, S Sasaki, ES Lee… - International Journal …, 2021 - Wiley Online Library
Background Atopic dermatitis (AD) is an allergic disease that affects individuals of various
ages. Recently, the IL‐4/13 inhibitor dupilumab has gained regulatory approval for clinical use …

A self‐directed home yoga programme for women with breast cancer during chemotherapy: a feasibility study

…, K Yagasaki, H Yamauchi, T Yamauchi… - … Journal of Nursing …, 2016 - Wiley Online Library
Recent studies suggest yoga as a promising approach for improving the cognitive function
of cancer survivors. We studied whether a self‐directed home yoga programme was feasible …

Mixture formation of fuel injection systems in gasoline engines

T Nogi, Y Ohyama, T Yamauchi, H Kuroiwa - SAE transactions, 1988 - JSTOR
Mixture formation technology for gasoline engine multipoint fuel injection systems has been
investigated. The fuel injector's spray, the volatility of droplets floating in the air flow, the …

Association between chronic kidney disease and mortality in stage IV cancer

…, O Takahashi, M Nakayama, T Yamauchi… - International Journal of …, 2020 - Springer
Background Chronic kidney disease (CKD) is known to be associated with cancer mortality.
However, no study has considered the well-known cancer prognostic factors, ECOG …

[HTML][HTML] Characteristics of taste alterations in people receiving taxane-based chemotherapy and their association with appetite, weight, and quality of life

M Kaizu, H Komatsu, H Yamauchi, T Yamauchi… - Supportive Care in …, 2021 - Springer
Purpose There is limited evidence on the effect of chemotherapy-associated taste alteration.
This study aimed to evaluate taste alteration characteristics in patients receiving taxane-…