Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
…, O Ishikawa, S Ariizumi, M Yamamoto, T Yamada… - Nature …, 2012 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death
worldwide. We sequenced and analyzed the whole genomes of 27 HCCs, 25 of which were …
worldwide. We sequenced and analyzed the whole genomes of 27 HCCs, 25 of which were …
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer
…, T Okusaka, M Kubo, S Marubashi, T Yamada… - Nature …, 2016 - nature.com
Liver cancer, which is most often associated with virus infection, is prevalent worldwide, and
its underlying etiology and genomic structure are heterogeneous. Here we provide a whole-…
its underlying etiology and genomic structure are heterogeneous. Here we provide a whole-…
A novel image‐guided surgery of hepatocellular carcinoma by indocyanine green fluorescence imaging navigation
K Gotoh, T Yamada, O Ishikawa… - Journal of surgical …, 2009 - Wiley Online Library
Background and Objectives The clear delineation between tumor and normal tissue is ideal
for real‐time surgical navigation imaging. We present a novel indocyanine green (ICG) …
for real‐time surgical navigation imaging. We present a novel indocyanine green (ICG) …
Detection of K-ras gene mutations in plasma DNA of patients with pancreatic adenocarcinoma: correlation with clinicopathological features.
T Yamada, S Nakamori, H Ohzato, S Oshima… - Clinical cancer research …, 1998 - AACR
We investigated the presence of K-ras gene mutation in plasma DNA and assessed its
clinical value in patients with pancreatic adenocarcinoma. Mutations in codon 12 of the K-ras …
clinical value in patients with pancreatic adenocarcinoma. Mutations in codon 12 of the K-ras …
Hepatocellular carcinoma arising from non-cirrhotic nonalcoholic steatohepatitis
…, R Ishihara, T Matsunaga, K Gotoh, T Yamada… - Journal of …, 2009 - Springer
Purpose Characteristics of hepatocellular carcinoma (HCC) complicating nonalcoholic
steatohepatitis (NASH) are still controversial. Most NASH related HCCs are believed to develop …
steatohepatitis (NASH) are still controversial. Most NASH related HCCs are believed to develop …
Detection of sentinel node in gastric cancer surgery by indocyanine green fluorescence imaging: comparison with infrared imaging
…, N Miyoshi, M Hiratsuka, K Kishi, T Yamada… - Annals of surgical …, 2008 - Springer
Background Secure methods for clinical detection of the sentinel node (SN) are in great
demand to avoid unnecessary resection. This was a clinical exploration/feasibility study of a …
demand to avoid unnecessary resection. This was a clinical exploration/feasibility study of a …
[HTML][HTML] Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity
…, H Aikata, H Ohdan, S Marubashi, T Yamada… - Nature …, 2015 - nature.com
Intrahepatic cholangiocarcinoma and combined hepatocellular cholangiocarcinoma show
varying degrees of biliary epithelial differentiation, which can be defined as liver cancer …
varying degrees of biliary epithelial differentiation, which can be defined as liver cancer …
Risk of recurrence in a long-term follow-up after surgery in 417 patients with hepatitis B-or hepatitis C-related hepatocellular carcinoma
YO Sasaki, T Yamada, H Tanaka, H Ohigashi… - Annals of …, 2006 - journals.lww.com
Objective: The aim of this study is to clarify the difference of risk of recurrence after hepatic
resection between patients with hepatitis B-and hepatitis C-related hepatocellular carcinoma (…
resection between patients with hepatitis B-and hepatitis C-related hepatocellular carcinoma (…
Preoperative gemcitabine-based chemoradiation therapy for resectable and borderline resectable pancreatic cancer
…, H Ohigashi, K Gotoh, S Marubashi, T Yamada… - Annals of …, 2013 - journals.lww.com
Objective: To evaluate the outcome of preoperative gemcitabine-based chemoradiation
therapy (CRT) for resectable and borderline resectable pancreatic cancer (PC), with a focus on …
therapy (CRT) for resectable and borderline resectable pancreatic cancer (PC), with a focus on …
Diagnosis of intrahepatic metastasis and multicentric carcinogenesis by microsatellite loss of heterozygosity in patients with multiple and recurrent hepatocellular …
…, H Nagano, M Sakon, Y Fujiwara, T Yamada… - Journal of …, 2003 - Elsevier
Background/Aims: The prognosis of hepatocellular carcinoma (HCC) is poor because of
frequent intrahepatic metastasis (IM) or multicentric carcinogenesis (MC). We compared the …
frequent intrahepatic metastasis (IM) or multicentric carcinogenesis (MC). We compared the …