User profiles for TAKESHI KANNO

Takeshi Kanno

Division of Gastroenterology, Tohoku University Graduate School of Medicine
Verified email at med.tohoku.ac.jp
Cited by 842

Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesis in Vitro

…, M Goto, K Yamaguchi, M Kuriyama, T Kanno… - …, 1998 - academic.oup.com
The morphogenesis and remodeling of bone depends on the integrated activity of osteoblasts
that form bone and osteoclasts that resorb bone. We previously reported the isolation of a …

Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin

…, K Irie, A Murakami, N Fujise, T Kanno… - Biochemical and …, 1998 - Elsevier
Osteoclasts are multinucleated cells that resorb bone. Osteoclastogenesis inhibitory factor (OCIF),
also called osteoprotegerin (OPG), acts as a naturally occurring decoy receptor for …

[HTML][HTML] Evidence-based clinical practice guidelines for peptic ulcer disease 2020

…, T Itoh, M Ito, J Iwamoto, T Okimoto, T Kanno… - Journal of …, 2021 - Springer
The Japanese Society of Gastroenterology (JSGE) revised the third edition of evidence-based
clinical practice guidelines for peptic ulcer disease in 2020 and created an English version…

Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis

A Mizuno, T Kanno, M Hoshi, O Shibata, K Yano… - Journal of bone and …, 2002 - Springer
Osteoclast differentiation factor, ODF, also called RANKL, TRANCE, or OPGL, is a key
molecule for osteoclast differentiation and activation, and is thought to act as a membrane-…

[HTML][HTML] Helicobacter pylori-negative, non-steroidal anti-inflammatory drug: negative idiopathic ulcers in Asia

K Iijima, T Kanno, T Koike… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Since the discovery of Helicobacter pylori (H. pylori) infection in the stomach, the bacteria
infection and non-steroidal anti-inflammatory drugs (NSAIDs) use had been considered to be …

Histopathology of incidental findings in cynomolgus monkeys (Macaca fascicularis) used in toxicity studies

J Sato, T Doi, T Kanno, Y Wako… - Journal of toxicologic …, 2012 - jstage.jst.go.jp
The purpose of our publication is to widely communicate pictures of spontaneous findings
occurring in cynomolgus monkeys. Focal lymphoplasmacytic infiltration is commonly seen in …

Peptic ulcers after the Great East Japan earthquake and tsunami: possible existence of psychosocial stress ulcers in humans

T Kanno, K Iijima, Y Abe, T Koike, N Shimada… - Journal of …, 2013 - Springer
Background Societal stress derived from an event that affects the whole society, eg, a
natural disaster, provides a unique, indirect way of determining the relationship between …

What is the prevalence of clinically significant endoscopic findings in subjects with dyspepsia? updated systematic review and meta-analysis

…, AH Mousavian, A Kasaeian, T Kanno… - Clinical …, 2023 - Elsevier
Background & Aims The prevalence of clinically significant endoscopic findings in people with
dyspepsia and understanding how symptoms can predict endoscopic pathology can help …

[HTML][HTML] The linoleic acid derivative DCP-LA selectively activates PKC-ɛ, possibly binding to the phosphatidylserine binding site

T Kanno, H Yamamoto, T Yaguchi, R Hi, T Mukasa… - Journal of lipid …, 2006 - ASBMB
This study examined the effect of 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid
(DCP-LA), a newly synthesized linoleic acid derivative with cyclopropane rings instead of …

Hyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice

T Kanno, A Tsuchiya, T Nishizaki - Behavioural brain research, 2014 - Elsevier
The present study investigated the relation of age-dependent spatial learning/memory impairment
and Tau phosphorylation in 5XFAD mice, a model of Alzheimer's disease. In the water …