User profiles for TAKAYUKI HARADA

Takayuki Harada 原田隆之

筑波大学、心理学教授
Verified email at human.tsukuba.ac.jp
Cited by 343

Microglia–Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration

T Harada, C Harada, S Kohsaka, E Wada… - Journal of …, 2002 - Soc Neuroscience
Activation of microglia commonly occurs in response to a wide variety of pathological stimuli
including trauma, axotomy, ischemia, and degeneration in the CNS. In the retina, prolonged …

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice

…, T Yamanishi, Y Sakai, H Kiyosawa, T Harada… - Nature …, 1999 - nature.com
The gracile axonal dystrophy (gad) mouse is an autosomal recessive mutant that shows
sensory ataxia at an early stage, followed by motor ataxia at a later stage 1. Pathologically, the …

[PDF][PDF] Modification of glial–neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration

T Harada, C Harada, N Nakayama, S Okuyama… - Neuron, 2000 - cell.com
Prolonged or high-intensity exposure to visible light leads to photoreceptor cell death. In this
study, we demonstrate a novel pathway of light-induced photoreceptor apoptosis involving …

Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron

…, YJ Sun, M Sakurai, T Harada… - Human molecular …, 2003 - academic.oup.com
Mammalian neuronal cells abundantly express a deubiquitylating enzyme, ubiquitin carboxy-terminal
hydrolase 1 (UCH L1). Mutations in UCH L1 are linked to Parkinson's disease as …

[HTML][HTML] The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma

T Harada, C Harada, K Nakamura… - The Journal of …, 2007 - Am Soc Clin Investig
Glaucoma, a progressive optic neuropathy due to retinal ganglion cell (RGC) degeneration,
is one of the leading causes of irreversible blindness. Although glaucoma is often …

Results of the COVID-19 mental health international for the general population (COMET-G) study

…, A Grau, V Groudeva, M Hagin, T Harada… - European …, 2022 - Elsevier
Introduction There are few published empirical data on the effects of COVID‐19 on mental
health, and until now, there is no large international study. Material and methods During the …

Functions of the two glutamate transporters GLAST and GLT-1 in the retina

T Harada, C Harada, M Watanabe… - Proceedings of the …, 1998 - National Acad Sciences
In the retina, the glutamate transporter GLAST is expressed in Müller cells, whereas the
glutamate transporter GLT-1 is found only in cones and various types of bipolar cells. To …

Spectroscopic visualization of vortex flows using dye‐containing nanofibers

A Tsuda, MA Alam, T Harada, T Yamaguchi… - Angewandte …, 2007 - Wiley Online Library
A vortex is a recognized example of macroscopic chirality [1] and one possible origin of chiral
symmetry-breaking in nature.[2–8] Compared with, for example, rheometric shear flows,[9] …

[HTML][HTML] Neuroprotection, growth factors and BDNF-TrkB signalling in retinal degeneration

…, K Namekata, X Guo, C Harada, T Harada - International journal of …, 2016 - mdpi.com
Neurotrophic factors play key roles in the development and survival of neurons. The potent
neuroprotective effects of neurotrophic factors, including brain-derived neurotrophic factor (…

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation

…, T Harada, L Liu, ME Lush, F Guignard, C Harada… - 2005 - journals.biologists.com
The gene responsible for neurofibromatosis type 1 (NF1) encodes a tumor suppressor that
functions as a negative regulator of the Ras proto-oncogene. Individuals with germline …