Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome
…, Y Kashikura, M Takamura, M Yoneda, T Shiraishi - Breast cancer, 2012 - Springer
Background Recently, the desmoplastic reaction has been implicated as having an important
function in epithelial solid tumor biology. There have been no reports showing the relativity …
function in epithelial solid tumor biology. There have been no reports showing the relativity …
Adoptive transfer of MAGE-A4 T-cell receptor gene-transduced lymphocytes in patients with recurrent esophageal cancer
…, S Kokura, H Naota, K Ohishi, T Shiraishi… - Clinical Cancer …, 2015 - AACR
Purpose: Preparative lymphodepletion, the temporal ablation of the immune system, has
been reported to promote persistence of transferred cells along with increased rates of tumor …
been reported to promote persistence of transferred cells along with increased rates of tumor …
[HTML][HTML] Tenascin C induces epithelial-mesenchymal transition–like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human …
…, N Hanamura, Y Kozuka, T Ogawa, T Shiraishi… - The American journal of …, 2011 - Elsevier
Tenascin C (TNC) is an extracellular matrix glycoprotein up-regulated in solid tumors. Higher
TNC expression is shown in invading fronts of breast cancer, which correlates with poorer …
TNC expression is shown in invading fronts of breast cancer, which correlates with poorer …
[HTML][HTML] Epigenetic regulation of androgen receptor gene expression in human prostate cancers
…, A Mizokami, H Ito, R Yatani, T Shiraishi - Laboratory …, 2000 - Elsevier
Epigenetic mechanisms including DNA methylation and histone deacetylation are thought
to play important roles in gene transcriptional inactivation. Heterogenous expression of …
to play important roles in gene transcriptional inactivation. Heterogenous expression of …
Presence of ras Oncogene Mutations and Human Papillomavirus DNA in Human Prostate Carcinomas
K Anwar, K Nakakuki, T Shiraishi, H Naiki, R Yatani… - Cancer research, 1992 - AACR
The frequency of H-ras, K-ras, and N-ras mutations and the presence of high-risk human
papillomavirus (HPV 16, 18, and 33) DNA were studied in 75 paraffin-embedded specimens …
papillomavirus (HPV 16, 18, and 33) DNA were studied in 75 paraffin-embedded specimens …
Three-dimensional cellular spheroid formation provides human prostate tumor cells with tissue-like features
…, Y Hirokawa, T Matsuzaki, T Shiraishi - Anticancer …, 2007 - ar.iiarjournals.org
Background: Alterations in the cellular biological responses were examined in a series of
LNCaP human prostate tumor cells growing under different conditions. Materials and Methods: …
LNCaP human prostate tumor cells growing under different conditions. Materials and Methods: …
Humoral immune responses in patients vaccinated with 1–146 HER2 protein complexed with cholesteryl pullulan nanogel
…, M Hirayama, Y Nagata, H Imai, T Shiraishi… - Cancer …, 2008 - Wiley Online Library
The CHP‐HER2 vaccine, comprising truncated 146HER2 protein complexed with nanogels
of cholesteryl pullulan (CHP), is a novel protein antigen vaccine that elicits 146HER2‐…
of cholesteryl pullulan (CHP), is a novel protein antigen vaccine that elicits 146HER2‐…
HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan
…, A Hiasa, H Naota, S Okumura, H Imai, T Shiraishi… - Clinical cancer …, 2006 - AACR
Purpose: We developed a complex of tumor antigen protein with a novel nanoparticle
antigen delivery system of cholesteryl pullulan (CHP). To target HER2 antigen, we prepared …
antigen delivery system of cholesteryl pullulan (CHP). To target HER2 antigen, we prepared …
Pretreatment serum testosterone level as a predictive factor of pathological stage in localized prostate cancer patients treated with radical prostatectomy
…, M Shimbo, M Inahara, A Komiya, T Ueda, T Shiraishi… - European urology, 2005 - Elsevier
OBJECTIVE:: Pretreatment serum level of testosterone (T) is a potential prognostic factor for
prostate cancer. The present study was conducted to evaluate the clinical significance of …
prostate cancer. The present study was conducted to evaluate the clinical significance of …
Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
…, T Kamataki, J Kawamura, R Yatani, T Shiraishi - Cancer letters, 2001 - Elsevier
Associations between genetic polymorphisms of CYP1A1, CYP1A2, CYP2E1, GSTM1 and
GSTT1 and prostate cancer (PCa) were analyzed in a case-control study of 315 individuals. …
GSTT1 and prostate cancer (PCa) were analyzed in a case-control study of 315 individuals. …