[HTML][HTML] ACE2 polymorphisms as potential players in COVID-19 outcome

…, BC Meireles Khayat, TM Thomaz Araújo… - PLoS …, 2020 - journals.plos.org
The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the
WHO in March 2020. Currently, there are more than 5 million cases worldwide, and the …

The role of piRNA and its potential clinical implications in cancer

CB Assumpção, DQ Calcagno, TMT Araújo… - …, 2015 - Future Medicine
Epigenetic mechanisms work in an orchestrated fashion to control gene expression in both
homeostasis and diseases. Among small noncoding RNAs, piRNAs seem to meet the …

Effects on DNA repair in human lymphocytes exposed to the food dye tartrazine yellow

BM Soares, TMT Araújo, JAB Ramos… - Anticancer …, 2015 - ar.iiarjournals.org
Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo
group. Studies about its genotoxic, cytotoxic and mutagenic effects are controversial and, in …

In vitro evaluation of the cytotoxic and genotoxic effects of artemether, an antimalarial drug, in a gastric cancer cell line (PG100)

…, HF Ribeiro, PCS Cardoso, TMT Araújo… - Journal of applied …, 2013 - Wiley Online Library
Artemisinin is a sesquiterpene lactone endoperoxide, obtained from Artemisia annua, and
extensively used as an antimalarial drug. Many studies have reported the genotoxic and …

[HTML][HTML] Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer

KC da Silva Oliveira, TMT Araújo… - World journal of …, 2016 - ncbi.nlm.nih.gov
Alterations in epigenetic control of gene expression play an important role in many diseases,
including gastric cancer. Many studies have identified a large number of upregulated …

Suicide journey of H. pylori through gastric carcinogenesis: the role of non-H. pylori microbiome and potential consequences for clinical practice

PP de Assumpção, TMT Araújo… - European Journal of …, 2019 - Springer
Despite being one of the most studied cancer-related infections, the relationship between
Helicobacter pylori infection and gastric adenocarcinoma (GC) remains, in some points, …

[HTML][HTML] GEJ cancers: gastric or esophageal tumors? searching for the answer according to molecular identity

…, NPC Dos Santos, RWM Junior, TMT Araújo… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The 7th edition of Union for International Cancer Control (UICC) staging system moved
gastroesophageal junction (GEJ) cancers from gastric to esophageal group. Since clinical …

[HTML][HTML] Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines

…, F Wisnieski, ES Chen, TMT Araújo… - World Journal of …, 2016 - ncbi.nlm.nih.gov
METHODS Four gastric cancer cell lines (ACP02, ACP03, AGP01 and PG100) underwent
chromosomal comparative genome hybridization and array comparative genome hybridization…

High-density array comparative genomic hybridization detects novel copy number alterations in gastric adenocarcinoma

AD Seabra, TMT Araújo, FAR MELLO… - Anticancer …, 2014 - ar.iiarjournals.org
Aim: To investigate frequent quantitative alterations of intestinal-type gastric adenocarcinoma.
Materials and Methods: We analyzed genome-wide DNA copy numbers of 22 samples …

[HTML][HTML] Treasures from trash in cancer research

…, JES de Souza, D de Souza Avelar, TMT Araújo… - Oncotarget, 2022 - ncbi.nlm.nih.gov
Introduction: Cancer research has significantly improved in recent years, primarily due to
next-generation sequencing (NGS) technology. Consequently, an enormous amount of …