User profiles for SUSAN MCDONNELL
Susan McDonnellUCD School of Chemical & Bioprocess Engineering Verified email at ucd.ie Cited by 3723 |
Lipopolysaccharide‐induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion
…, W Lu, AM Byrne, S McDonnell… - … journal of cancer, 2002 - Wiley Online Library
Endotoxin/lipopolysaccharide (LPS), a cell wall component of Gram‐negative bacteria, is a
potent inflammatory stimulus. We previously reported that LPS increased the growth of …
potent inflammatory stimulus. We previously reported that LPS increased the growth of …
Expression and localization of the matrix metalloproteinase pump‐1 (MMP‐7) in human gastric and colon carcinomas
S McDonnell, M Navre, RJ Coffey Jr… - Molecular …, 1991 - Wiley Online Library
The expression of members of the family of matrix‐degrading metalloproteinases (MMPs) is
believed to contribute to the complex process of invasion and metastasis. In this study, …
believed to contribute to the complex process of invasion and metastasis. In this study, …
[HTML][HTML] Exosomes from triple-negative breast cancer cells can transfer phenotypic traits representing their cells of origin to secondary cells
…, R Wallace, L Hughes, AM Friel, S McDonnell… - European journal of …, 2013 - Elsevier
BACKGROUND: Triple-negative breast cancer (TNBC) accounts for 15–20% of breast cancers
but is responsible for a disproportionate number of deaths. We investigated the relevance…
but is responsible for a disproportionate number of deaths. We investigated the relevance…
[HTML][HTML] Structure and expression of the human gene for the matrix metalloproteinase matrilysin.
M Gaire, Z Magbanua, S McDonnell, L McNeil… - Journal of Biological …, 1994 - Elsevier
Matrilysin, a member of the matrix metalloproteinase family, is structurally different from the
other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal …
other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal …
Modulation of Matrilysin Levels in Colon Carcinoma Cell Lines Affects Tumorigenicity in Vivo
JP Witty, S McDonnell, KJ Newell, P Cannon, M Navre… - Cancer Research, 1994 - AACR
The expression of the metalloproteinase matrilysin in the human colon carcinoma cell lines
SW480 and SW620 correlates with the ability of the SW620 cells to invade an artificial …
SW480 and SW620 correlates with the ability of the SW620 cells to invade an artificial …
Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity
…, S Chumsri, AM Burger, S McDonnell - Clinical & experimental …, 2008 - Springer
The process of tumour invasion and subsequent metastasis represents the most lethal aspect
of cancer. In this study the invasive and migratory activity of four human breast cancer cell …
of cancer. In this study the invasive and migratory activity of four human breast cancer cell …
Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies
…, A Byrne, AA Murphy, C Moss, S McDonnell… - …, 2005 - academic.oup.com
The incidence of melanoma is increasing rapidly, with advanced lesions generally failing to
respond to conventional chemotherapy. Here, we utilized DNA microarray-based gene …
respond to conventional chemotherapy. Here, we utilized DNA microarray-based gene …
Epidermal growth factor stimulation of stromelysin mRNA in rat fibroblasts requires induction of proto-oncogenes c-fos and c-jun and activation of protein kinase C
SE McDONNELL, LD Kerr… - Molecular and cellular …, 1990 - Am Soc Microbiol
Stromelysin (transin) is a secreted metalloprotease that is transcriptionally induced by a
variety of growth factors and oncogenes. We examined the necessity of specific secondary (…
variety of growth factors and oncogenes. We examined the necessity of specific secondary (…
The role of the matrix metalloproteinase stromelysin in the progression of squamous cell carcinomas
LM Matrisian, S McDonnell, DB Miller, M Navre… - The American journal of …, 1991 - Elsevier
The expression of the metalloproteinase stromelysin correlates with the progression of
chemically induced squamous cell carcinomas. We demonstrate that the expression of activated …
chemically induced squamous cell carcinomas. We demonstrate that the expression of activated …
Increased invasion and expression of MMP-9 in human colorectal cell lines by a CD44-dependent mechanism
D Murray, M Morrin, S McDonnell - Anticancer research, 2004 - ar.iiarjournals.org
Background: In order to investigate the interactions between MMPs and CD44 we stably
transfected a non-invasive colon cell line, SW480 with the cDNA for MMP-9 and investigated the …
transfected a non-invasive colon cell line, SW480 with the cDNA for MMP-9 and investigated the …