Introduction. Accumulating evidence suggests that enhanced inflammatory responses
contribute to the pathogenesis of postoperative cognitive dysfunction (POCD). Blood transfusion …

Sevoflurane, a commonly used inhaled anesthetic, can induce neuronal apoptosis in the
developing rodent brain and correlate with functional neurological impairment later in life. …

Few studies have examined the association between perioperative blood transfusion and
postoperative delirium (POD) in aged patients undergoing total hip replacement surgery. In …

Valproic acid (VPA) has been shown to exert anti-inflammatory and antioxidant effects in a
range of diseases including septic shock. However, the effects of VPA on lipopolysaccharide (…

We investigated whether mild hypothermia combined with sodium hydrosulfide treatment
during resuscitation improves neuron survival following cerebral ischemia-reperfusion injury …

Sepsis-associated encephalopathy (SAE) is a frequent complication in critically ill patients
and is associated with long-term cognitive impairments. However, the pathophysiology …

Background Both hydrogen sulphide (H 2 S) and mild hypothermia have been reported to
prevent brain damage caused by reperfusion assault through regulating the N-methyl-D-…

The present study aimed to find whether PROX1 is expressed in small cell lung cancer (SCLC)
cell lines, and whether PROX1 knockdown with shRNA via lentivirus resulted in …

Seawater drowning-induced acute lung injury (ALI) is a serious clinical condition characterized
by increased alveolar-capillary permeability, excessive inflammatory responses, and …

Background: The potential immunosuppressant effects of opioids might have clinical implications.
The effects of endomorphins (EMs) and ohmefentanyl (OMF) on cultured rat peritoneal …