Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and-9 and Vascular Endothelial …

SS Lin, KC Lai, SC Hsu, JS Yang, CL Kuo, JP Lin… - Cancer letters, 2009 - Elsevier
It is well known that matrix metalloproteinases (MMPs) act an important role in the invasion,
metastasis and angiogenesis of cancer cells. Agents suppressed the MMPs could inhibited …

Quercetin inhibits migration and invasion of SAS human oral cancer cells through inhibition of NF-κB and matrix metalloproteinase-2/-9 signaling pathways

WW Lai, SC Hsu, FS Chueh, YY Chen… - Anticancer …, 2013 - ar.iiarjournals.org
Quercetin, a principal flavanoid compound in onions, has been shown to possess a wide
spectrum of pharmacological properties, including anticancer activities. Our earlier study …

Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen …

KC Lai, AC Huang, SC Hsu, CL Kuo… - Journal of agricultural …, 2010 - ACS Publications
Benzyl isothiocyanate (BITC), a component of dietary cruciferous vegetables, has antioxidant
and anticancer properties. In this study, we show for the first time the antimetastatic effects …

Anticancer potential of emodin

SC Hsu, JG Chung - BioMedicine, 2012 - Elsevier
Traditional Chinese Medicine (TCM) is widely used in clinical research due to its low toxicity,
low number of side effects, and low cost. Many components of common fruits and …

Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix …

KC Lai, SC Hsu, CL Kuo, JS Yang, CY Ma… - Environmental …, 2013 - Wiley Online Library
Diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS) are major organosulfur
compounds exiting in garlic (Allium sativum). These compounds are reported to exhibit …

Antitumor activity of capsaicin on human colon cancer cells in vitro and colo 205 tumor xenografts in vivo

…, JS Yang, YY Yang, JY Liu, SC Hsu… - Journal of agricultural …, 2010 - ACS Publications
Capsaicin was reported to inhibit cancer cell growth. The aim of this study was to evaluate the
antitumor potential of capsaicin by studying antitumor activity in vitro as well as in vivo. The …

The role of Ca2+ in baicalein-induced apoptosis in human breast MDA-MB-231 cancer cells through mitochondria-and caspase-3-dependent pathway

JH Lee, YC Li, SW Ip, SC Hsu, NW Chang… - Anticancer …, 2008 - ar.iiarjournals.org
Baicalein was investigated for tumor cell-specific cytotoxicity, apoptosis-inducing activity
and signal pathway against the MDA-MB-231 human breast cancer cell line. After the MDA-MB-…

Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer …

JC Chen, KW Lu, ML Tsai, SC Hsu, CL Kuo, JS Yang… - Oral oncology, 2009 - Elsevier
Gypenosides (Gyp), a component of Gynostemma pentaphyllum Makino, was selected for
examining the effects on the cell viability, cell cycle and induction of apoptosis in human …

Diallyl trisulfide inhibits migration, invasion and angiogenesis of human colon cancer HT‐29 cells and umbilical vein endothelial cells, and suppresses murine …

KC Lai, SC Hsu, JS Yang, CC Yu… - Journal of cellular …, 2015 - Wiley Online Library
Angiogenesis inhibitors are beneficial for the prevention and treatment of angiogenesis‐dependent
diseases including cancer. We examined the cytotoxic, anti‐metastatic, anti‐cancer …

Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK‐Hep1 cells through the inhibitions of NF‐kB and matrix metalloproteinase‐2/‐9 …

YY Chen, HF Lu, SC Hsu, CL Kuo… - Environmental …, 2015 - Wiley Online Library
Metastasis plays an important role in mortality of cancer patients. Migration and invasion are
the major characteristics of tumor metastasis. The induction of matrix metalloproteinases (…