[HTML][HTML] Efficacy and safety of short-term therapy with indigo naturalis for ulcerative colitis: an investigator-initiated multicenter double-blind clinical trial
K Uchiyama, S Takami, H Suzuki, K Umeki… - PLoS …, 2020 - journals.plos.org
Introduction Indigo naturalis (IN) is a blue pigment extracted from Assam indigo and other
plants and has been confirmed to be highly effective for ulcerative colitis (UC) treatment in …
plants and has been confirmed to be highly effective for ulcerative colitis (UC) treatment in …
[HTML][HTML] Dendritic cell-based cancer immunotherapy for colorectal cancer
…, T Kanai, Z Ito, K Saito, S Takami… - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common cancers and a leading cause of cancer-related
mortality worldwide. Although systemic therapy is the standard care for patients with …
mortality worldwide. Although systemic therapy is the standard care for patients with …
Prognostic markers for patient outcome following vaccination with multiple MHC Class I/II-restricted WT1 peptide-pulsed dendritic cells plus chemotherapy for …
…, Y Hirano, Z Ito, H Kobayashi, S Takami… - Anticancer …, 2015 - ar.iiarjournals.org
Background/Aim: Treatment combining dendritic cells (DCs) pulsed with three types of major
histocompatibility complex (MHC) class I and II (DC/WT1-I/II)-restricted Wilms' tumor 1 (WT1…
histocompatibility complex (MHC) class I and II (DC/WT1-I/II)-restricted Wilms' tumor 1 (WT1…
[HTML][HTML] A prospective study evaluating metabolic capacity of thiopurine and associated adverse reactions in Japanese patients with inflammatory bowel disease (IBD)
S Odahara, K Uchiyama, T Kubota, Z Ito, S Takami… - PLoS …, 2015 - journals.plos.org
Azathioprine (AZA) is frequently used in patients with inflammatory bowel disease (IBD).
However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the …
However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the …
[HTML][HTML] Production of corticotropin-releasing factor and urocortin from human monocyte-derived dendritic cells is stimulated by commensal bacteria in intestine
…, H Komita, Z Ito, H Kobayashi, S Takami… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To examine whether commensal bacteria are a contributing cause of stress-related
mucosal inflammation. METHODS: Human peripheral blood monocyte-derived dendritic cells (…
mucosal inflammation. METHODS: Human peripheral blood monocyte-derived dendritic cells (…
[HTML][HTML] Prognostic significance of plasma interleukin-6/-8 in pancreatic cancer patients receiving chemoimmunotherapy
…, Z Ito, T Kanai, K Saito, S Takami… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To investigate the association of plasma levels of interleukin (IL)-6 and-8 with Wilms’
tumor 1 (WT1)-specific immune responses and clinical outcomes in patients with pancreatic …
tumor 1 (WT1)-specific immune responses and clinical outcomes in patients with pancreatic …
Fatty acids as useful serological markers for crohn's disease
Z Ito, K Uchiyama, S Odahara, S Takami, K Saito… - Digestive …, 2018 - karger.com
Background: We have previously reported that patients with Crohn’s disease (CD) have a
very specific erythrocyte membrane phospholipid fatty acid profile. The findings of this study …
very specific erythrocyte membrane phospholipid fatty acid profile. The findings of this study …
[HTML][HTML] Analysis of the NUDT15 gene and metabolites of azathioprine in Japanese patients with inflammatory bowel disease
…, Y Inoue, T Kubota, S Odahara, Y Ohtaki, S Takami… - BMC …, 2023 - Springer
Background Thiopurines continue to play an important role in the treatment of inflammatory
bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. …
bowel disease (IBD). It is well known that thiopurines can cause several adverse reactions. …
FADS2 and ELOVL6 mutation frequencies in Japanese Crohn's disease patients
Y Motoi, Z Ito, S Suzuki, S Takami, K Matsuo… - Drug Discoveries & …, 2019 - jstage.jst.go.jp
Crohn's disease (CD) development is thought to involve genetic factors related to immune
response as well as environmental factors, such as intestinal bacteria and diet, though no …
response as well as environmental factors, such as intestinal bacteria and diet, though no …
Monitoring of Substrate and Epilayer Surfaces by Mirror Projection Electron Microscope
…, M Miyata, N Noguchi, S Takami… - Materials Science …, 2019 - Trans Tech Publ
4H-SiC surfaces before and after epitaxial growth (substrate and epitaxial layer surfaces) were
investigated by mirror projection electron microscopy (MPJ) and atomic force microscopy (…
investigated by mirror projection electron microscopy (MPJ) and atomic force microscopy (…