User profiles for SERGIU-BOGDAN CATRINA

Sergiu Catrina

Verified email at ki.se
Cited by 4584

Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

…, VG Sunkari, O Savu, AI Catrina… - Proceedings of the …, 2008 - National Acad Sciences
Relative hypoxia is essential in wound healing since it normally plays a pivotal role in regulation
of all the critical processes involved in tissue repair. Hypoxia-inducible factor (HIF) 1α is …

Hyperglycemia regulates hypoxia-inducible factor-1α protein stability and function

SB Catrina, K Okamoto, T Pereira, K Brismar… - Diabetes, 2004 - Am Diabetes Assoc
Hyperglycemia and hypoxia are suggested to play essential pathophysiological roles in the
complications of diabetes, which may result from a defective response of the tissues to low …

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

…, K Tyson, S Rapecki, K Lundberg, SB Catrina… - Annals of the …, 2016 - ard.bmj.com
Objectives Rheumatoid arthritis (RA)-specific anti-citrullinated protein/peptide antibodies (ACPAs)
appear before disease onset and are associated with bone destruction. We aimed to …

[HTML][HTML] Hypoxia and hypoxia-inducible factors in diabetes and its complications

SB Catrina, X Zheng - Diabetologia, 2021 - Springer
Hypoxia-inducible factors (HIFs) are the key regulators of oxygen homeostasis in response
to hypoxia. In diabetes, multiple tissues are hypoxic but adaptive responses to hypoxia are …

[HTML][HTML] MicroRNA-132 enhances transition from inflammation to proliferation during wound healing

…, E Sonkoly, K Chowdhury, SB Catrina… - The Journal of …, 2015 - Am Soc Clin Investig
Wound healing is a complex process that is characterized by an initial inflammatory phase
followed by a proliferative phase. This transition is a critical regulatory point; however, the …

Hyperbaric oxygen therapy activates hypoxia‐inducible factor 1 (HIF‐1), which contributes to improved wound healing in diabetic mice

…, K Brismar, O Velazquez, SB Catrina - Wound Repair and …, 2015 - Wiley Online Library
Abstract Hyperbaric oxygen ( HBO ) therapy has been used as an adjunctive therapy for
diabetic foot ulcers, although its mechanism of action is not completely understood. Recently, it …

Disturbed hypoxic responses as a pathogenic mechanism of diabetic foot ulcers

SB Catrina, X Zheng - Diabetes/metabolism research and …, 2016 - Wiley Online Library
Diabetic foot ulceration (DFU) is a chronic complication of diabetes that is characterized by
impaired wound healing in the lower extremities. DFU remains a major clinical challenge …

LeucoPatch system for the management of hard-to-heal diabetic foot ulcers in the UK, Denmark, and Sweden: an observer-masked, randomised controlled trial

…, D Maguire, T Aung, H Holmer, SB Catrina… - The Lancet Diabetes & …, 2018 - thelancet.com
Background The LeucoPatch device uses bedside centrifugation without additional reagents
to generate a disc comprising autologous leucocytes, platelets, and fibrin, which is applied …

Clinical and immunological characteristics of autoimmune Addison disease: a nationwide Swedish multicenter study

…, P Olcen, O Winqvist, SB Catrina… - The Journal of …, 2017 - academic.oup.com
Context: Studies of the clinical and immunological features of autoimmune Addison disease
(AAD) are needed to understand the disease burden and increased mortality. Objective: To …

Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes

…, J Grünler, V Peters, CP Schmitt, SB Catrina… - Amino acids, 2012 - Springer
Diabetes mellitus (DM) is a progressive disorder with severe late complications. Normal wound
healing involves a series of complex and well-orchestrated molecular events dictated by …