Pattern analysis, not simplified algorithms, is the most reliable method for teaching dermoscopy for melanoma diagnosis to residents in dermatology

P Carli, E Quercioli, S Sestini, M Stante… - British Journal of …, 2003 - academic.oup.com
Background Simplified algorithms for dermoscopy in melanoma diagnosis were developed
in order to facilitate the use of this technique by non‐experts. However, little is known about …

Estrogen receptor expression in cutaneous melanoma: a real-time reverse transcriptase–polymerase chain reaction and immunohistochemical study

…, A Gozzini, P Aragona, A Tanini, S Sestini… - Archives of …, 2009 - jamanetwork.com
Objective To evaluate estrogen receptor (ER) expression in human melanoma tissues and
in the adjacent healthy skin with the aim of explaining whether theERα:ERβexpression ratio …

[HTML][HTML] Factors affecting sentinel node metastasis in thin (T1) cutaneous melanomas: development and external validation of a predictive nomogram

…, C Del Forno, L Borgognoni, S Sestini… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
PURPOSE Thin melanomas (T1;≤ 1 mm) constitute 70% of newly diagnosed cutaneous
melanomas. Regional node metastasis determined by sentinel node biopsy (SNB) is an …

Dendritic cells recruitment in melanoma metastasis treated by electrochemotherapy

G Gerlini, S Sestini, P Di Gennaro, C Urso… - Clinical & experimental …, 2013 - Springer
Electrochemotherapy (ECT) is a novel treatment for recurrent or in-transit unresectable
melanoma metastases based on the administration of anti-neoplastic drugs followed by cancer …

Prediction of non-sentinel node status in patients with melanoma and positive sentinel node biopsy: an Italian Melanoma Intergroup (IMI) study

…, LG Campana, L Borgognoni, S Sestini… - Annals of Surgical …, 2018 - Springer
Background and Purpose Approximately 20% of melanoma patients harbor metastases in
non-sentinel nodes (NSNs) after a positive sentinel node biopsy (SNB), and recent evidence …

[HTML][HTML] Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth

…, F Poggialini, C Vagaggini, G Giannini, S Sestini… - Pharmacological …, 2023 - Elsevier
Aberrant activation of Hedgehog (HH) signaling in cancer is the result of genetic alterations
of upstream pathway components (canonical) or other oncogenic mechanisms (noncanonical…

[HTML][HTML] Insights into Genetic Susceptibility to Melanoma by Gene Panel Testing: Potential Pathogenic Variants in ACD, ATM, BAP1, and POT1

…, P Chiurazzi, G Maccanti, S Manoukian, S Sestini… - Cancers, 2020 - mdpi.com
The contribution of recently established or candidate susceptibility genes to melanoma missing
heritability has yet to be determined. Multigene panel testing could increase diagnostic …

Dermoscopy for “true” amelanotic melanoma: a clinical dermoscopic-pathologic case study

V de Giorgi, S Sestini, D Massi, V Maio… - Journal of the American …, 2006 - Elsevier
Completely amelanotic melanomas are rare and therefore often misclassified, with tragic
consequences for patients. The use of dermoscopy for these lesions has not been validated yet …

Keratinocyte growth factor receptors

V De Giorgi, S Sestini, D Massi, I Ghersetich, T Lotti - Dermatologic clinics, 2007 - Elsevier
Modulation of the number of functional growth factor receptors on the epithelial cell surface
that is exposed to the action of cognate ligands represents a key strategy in cellular …

Efficacy of electrochemotherapy in the treatment of cutaneous melanoma metastases and rare non-melanoma skin cancer

…, R Gelli, V Giannotti, F Bellucci, S Sestini - Anticancer …, 2020 - ar.iiarjournals.org
Background. We aimed to verify the clinical efficacy and safety of the electrochemotherapy in
melanoma metastases and in cases of rare non-melanoma tumors that were difficult to treat …