User profiles for SEONG-HOON PARK
Seong-Hoon ParkKorea Institute of Toxicology Verified email at kitox.re.kr Cited by 4284 |
[PDF][PDF] Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress
Genetic deletion of the mitochondrial deacetylase sirtuin-3 (Sirt3) results in increased
mitochondrial superoxide, a tumor-permissive environment, and mammary tumor development. …
mitochondrial superoxide, a tumor-permissive environment, and mammary tumor development. …
[PDF][PDF] SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
The sirtuin gene family (SIRT) is hypothesized to regulate the aging process and play a role
in cellular repair. This work demonstrates that SIRT3 −/− mouse embryonic fibroblasts (MEFs…
in cellular repair. This work demonstrates that SIRT3 −/− mouse embryonic fibroblasts (MEFs…
[PDF][PDF] SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
Members of sirtuin family regulate multiple critical biological processes, yet their role in
carcinogenesis remains controversial. To investigate the physiological functions of SIRT2 in …
carcinogenesis remains controversial. To investigate the physiological functions of SIRT2 in …
Colloidal gold nanoparticles as a blood-pool contrast agent for X-ray computed tomography in mice
…, SY Kim, SJ Byun, KW Kim, SH Park… - Investigative …, 2007 - journals.lww.com
Objectives: To present the pharmacokinetics and computed tomographic imaging efficacy of
colloidal gold nanoparticles (AuNPs) as a blood-pool agent for x-ray computed tomography (…
colloidal gold nanoparticles (AuNPs) as a blood-pool agent for x-ray computed tomography (…
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells
Pyruvate dehydrogenase E1α (PDHA1) is the first component enzyme of the pyruvate
dehydrogenase (PDH) complex that transforms pyruvate, via pyruvate decarboxylation, into acetyl-…
dehydrogenase (PDH) complex that transforms pyruvate, via pyruvate decarboxylation, into acetyl-…
[HTML][HTML] Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress
A fundamental observation in biology is that mitochondrial function, as measured by increased
reactive oxygen species (ROS), changes significantly with age, suggesting a potential …
reactive oxygen species (ROS), changes significantly with age, suggesting a potential …
Radiologic and clinical findings of Behçet disease: comprehensive review of multisystemic involvement
Behçet disease is a chronic, relapsing, systemic disorder of unknown etiology, characterized
by recurrent oral and genital ulcers, uveitis, and other clinical manifestations in multiple …
by recurrent oral and genital ulcers, uveitis, and other clinical manifestations in multiple …
The person in the purchase: narcissistic consumers prefer products that positively distinguish them.
SY Lee, AP Gregg, SH Park - Journal of Personality and Social …, 2013 - psycnet.apa.org
Narcissists, who seek keenly to self-enhance, strive to positively distinguish themselves.
Might they therefore be inclined to purchase consumer products that enable them to do so? …
Might they therefore be inclined to purchase consumer products that enable them to do so? …
Loss of NAD-dependent protein deacetylase sirtuin-2 alters mitochondrial protein acetylation and dysregulates mitophagy
Aims: Sirtuins connect energy generation and metabolic stress to the cellular acetylome.
Currently, only the mitochondrial sirtuins (SIRT3–5) and SIRT1 have been shown to direct …
Currently, only the mitochondrial sirtuins (SIRT3–5) and SIRT1 have been shown to direct …
[HTML][HTML] Sirt3, mitochondrial ROS, ageing, and carcinogenesis
One fundamental observation in cancer etiology is that the rate of malignancies in any
mammalian population increases exponentially as a function of age, suggesting a mechanistic …
mammalian population increases exponentially as a function of age, suggesting a mechanistic …