[HTML][HTML] PPARα Expression Protects Male Mice from High Fat–Induced Nonalcoholic Fatty Liver1–3

MA Abdelmegeed, SH Yoo, LE Henderson… - The Journal of …, 2011 - Elsevier
Emerging evidence suggests that the lack of PPARα enhances hepatic steatosis and
inflammation in Ppara-null mice when fed a high-fat diet (HFD). Thus, the aim of this study was to …

[PDF][PDF] In vivo consequences of liver‐specific interleukin‐22 expression in mice: Implications for human liver disease progression

…, L Feigenbaum, H Li, S Yin, SH Ki, SH Yoo… - …, 2011 - Wiley Online Library
Interleukin‐22 (IL‐22), which acts as either a proinflammatory or anti‐inflammatory cytokine
in various disease models, is markedly up‐regulated in chronic liver diseases, including …

Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

MA Abdelmegeed, A Banerjee, SH Yoo, S Jang… - Journal of …, 2012 - Elsevier
BACKGROUND & AIMS: Ethanol-inducible cytochrome P450 2E1 (CYP2E1) activity contributes
to oxidative stress. However, CYP2E1 may have an important role in the pathogenesis …

CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis

MA Abdelmegeed, A Banerjee, S Jang, SH Yoo… - Free Radical Biology …, 2013 - Elsevier
Ethanol-inducible cytochrome P450 2E1 (CYP2E1) contributes to increased oxidative stress
and steatosis in chronic alcohol-exposure models. However, its role in binge ethanol-…

[HTML][HTML] Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability

…, AH Jeon, MT Park, SJ Lee, CM Kang, HS Lee, SH Yoo… - Cancer cell, 2003 - cell.com
In this study, we show that the formation of polyploidy following sustained mitotic checkpoint
activation appears to be preceded by the ubiquitin-dependent proteolysis of hBubR1. In …

Fructose promotes leaky gut, endotoxemia, and liver fibrosis through ethanol‐inducible cytochrome P450‐2E1–mediated oxidative and nitrative stress

YE Cho, DK Kim, W Seo, B Gao, SH Yoo, BJ Song - Hepatology, 2021 - journals.lww.com
Fructose intake is known to induce obesity, insulin resistance, metabolic syndrome, and
nonalcoholic fatty liver disease (NAFLD). We aimed to evaluate the effects of fructose drinking …

[HTML][HTML] χ-separation: Magnetic susceptibility source separation toward iron and myelin mapping in the brain

HG Shin, J Lee, YH Yun, SH Yoo, J Jang, SH Oh… - Neuroimage, 2021 - Elsevier
Obtaining a histological fingerprint from the in-vivo brain has been a long-standing target of
magnetic resonance imaging (MRI). In particular, non-invasive imaging of iron and myelin, …

Expression of caveolin-1 is associated with poor prognosis of patients with squamous cell carcinoma of the lung

SH Yoo, YS Park, HR Kim, SW Sung, JH Kim, YS Shim… - Lung cancer, 2003 - Elsevier
Background: Caveolin-1, as a major component of caveolae, is involved in the regulation of
cell cycle by impacting various signaling pathways. Previous studies of caveolin-1 in cancer …

[HTML][HTML] Coronal alignment of the lower limb and the incidence of constitutional varus knee in Korean females

MH Song, SH Yoo, SW Kang, YJ Kim… - Knee surgery & …, 2015 - ncbi.nlm.nih.gov
Purpose In total knee arthroplasty (TKA), it is important to restore neutral mechanical alignment.
The purpose of this study was to assess whether the lower limb alignment is neutral in …

Apoptosis of enterocytes and nitration of junctional complex proteins promote alcohol-induced gut leakiness and liver injury

YE Cho, LR Yu, MA Abdelmegeed, SH Yoo… - Journal of hepatology, 2018 - Elsevier
Background & Aims Binge alcohol exposure causes gut leakiness, contributing to increased
endotoxemia and inflammatory liver injury, although the molecular mechanisms are still …