Autophagy is a catabolic process involved in cell death and in cell protective mechanism.
Autophagic cell death is differentiated from apoptosis by the presence of double or multiple-…

Colorectal cancer (CRC) patients frequently experience disease recurrence and distant
metastasis. This study aimed to identify prognostic indicators, including individual responses to …

AIM: To investigate alternative or subordinate pathways involved in colorectal tumorigenesis
and tumor growth, possibly determining at-risk populations and predicting responses to …

Objectives: To evaluate the association of microsatellite instability (MSI) with clinicopathologic
features and oncologic outcomes in patients with poorly differentiated colorectal cancer (…

Autophagy plays complex roles in tumor initiation and development, and the expression of
autophagy-related genes (ATGs) is differentially regulated in various cancer cells, depending …

Background and Aim: The aim of the present study was to evaluate associations between
mismatch repair (MMR) status and clinicopathological characteristics and prognosis using …

The present study aimed to identify molecules associated with lymphovascular invasion (LVI)
and perineural invasion (PNI) and to examine their biological behavior in colorectal cancer …

To characterize the mutation profiles of colorectal cancer (CRC) primary tumors (PTs) and
liver metastases (CLMs), we performed both whole-exome and RNA sequencing. Ten …

Approximately half of colorectal cancer (CRC) patients experience disease recurrence and
metastasis, and these individuals frequently fail to respond to treatment due to their clinical …

Purpose The ability to predict individual responsiveness to cancer therapy is urgently needed.
This is particularly true for patients with locally advanced rectal cancer (LARC) because a …