Expression of CD40 correlates negatively with overall and progression-free survival of low-and high-grade gliomas

JM Werner, S Kuhl, K Ulrich, B Krischek, P Stavrinou… - World Neurosurgery, 2019 - Elsevier
Background Low-grade gliomas (LGGs) are known to progress to glioblastoma (GBM),
decreasing the chances of survival. The tumor necrosis factor receptor CD40 and its ligand …

Death receptor 6 (DR6) is overexpressed in astrocytomas

S Stegmann, JM Werner, S Kuhl, G Roehn… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Death receptor 6 (DR6) is a member of the tumor necrosis factor receptor
superfamily. The expression of DR6 is elevated in different kinds of tumors including ovarian, …

Expression of FAS-L differs from primary to relapsed low-grade gliomas and predicts progression-free survival

JM Werner, S Kuhl, P Stavrinou, G Roehn… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: The tumor necrosis factor FAS is overexpressed in high-grade gliomas (HGG).
Only little is known about FAS or FAS ligand (FAS-L) in low-grade gliomas (LGG). We …

Death receptor 6 as a prognostic marker in low-grade glioma

SK Stegmann, S Kuhl, NG Im, DT Diem-Dinh… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Low-grade gliomas (LGG) are heterogenous tumours, causing variable
survivals in patients. Identifying molecular markers for a more accurate prognosis is, therefore, …

Expression of ENO1 is up-regulated in low-grade glioma and positively correlated with meningioma grade

DTD Dinh, S Kuhl, L Goertz, R Goldbrunner… - Anticancer …, 2022 - ar.iiarjournals.org
Background: α-Enolase (ENO1) is a glycolytic enzyme involved in the Warburg effect which
cancer cells utilize to satisfy their higher need for nutrients. Up-regulation of ENO1 has been …

[HTML][HTML] TERT and its binding protein: overexpression of GABPA/B in high grade gliomas

E Papazacharias, S Kuhl, G Röhn, L Görtz… - Oncotarget, 2021 - ncbi.nlm.nih.gov
Enhanced expression of TERT in gliomas is a result of two hotspot mutations, C228T and
C250T, at the promoter region. GA-binding proteins selectively bind at these positions, …

BIOM-01. MTH1 expression is upregulated in brain metastases of malignant melanoma

M Timmer, S Kuhl, R Goldbrunner - Neuro-Oncology, 2021 - ncbi.nlm.nih.gov
MuT Homolog1 (MTH1) is an enzyme involved in DNA repair in normal cells and is often up-regulated
in cancer cells. The enzyme catalyses the hydrolysis of oxidised dNTPs, to …

[PDF][PDF] Expression of YAP and TAZ in brain tumors from different age groups

L Hero, J Dicke, S Kuhl, R Goldbrunner, M Timmer - junge-erwachsene-mit-krebs.de
Brain tumors from different age groups come with variable characteristics. They differ in their
molecular characteristics and in the patients’ outcome. There is few research on the …

[PDF][PDF] YAP and TAZ expression in benign pediatric brain tumors with high levels in choroid plexus papilloma

L Hero, S Kuhl, J Dicke, R Goldbrunner, M Timmer - junge-erwachsene-mit-krebs.de
Yes-associated protein (YAP) and its paralogue Transcriptional co-activator with PDZ-binding
motif (TAZ) are transcriptional co-activators affected primarily by mechanotransduction of …

The Current Status of Breast MR Imaging Part I. Choice of Technique, Image Interpretation, Diagnostic Accuracy, and Transfer to Clinical Practice1

C Kuhl - Radiology, 2007 - pubs.rsna.org
Compared with mammography and breast ultrasonography, contrast material–enhanced
magnetic resonance (MR) imaging is a breast imaging technique that offers not only …