To elucidate sleep disturbances in the etiology of peptic ulcers, the prevalence of peptic
ulcer disease was compared among shift workers and daytime workers. The subjects (N=11,657…

BACKGROUND Early diagnosis and complete removal of pancreatic adenocarcinoma (PC)
is essential to improve its poor prognosis. It is necessary to find PC when it is small and at an …

A new pancreatic tumor, called mucin‐producing tumor, has received great attention in
Japan. These tumors are found inside the pancreatic duct and produce large quantities of …

Teprenone, an anti-ulcer drug, has been reported to promote the healing of acetic acid-induced
chronic gastric ulcers in rats by stimulating gastric mucus synthesis and secretion. …

Background: Lentinan (LNT) is an immune adjuvant medicine for advanced gastric cancer
in Japan. Recently, an oral formulation of superfine dispersed lentinan (SDL) has become …

Results Thirty-six patients were eligible among 40 enrolled patients. Median survival time of
eligible patients was 13.6 months (95% confidence interval, 8.7-18.9 months). Survival times …

Sucralfate is a basic aluminum salt of a sulfated disaccharide. In this study, patients with
gastric ulcer were given oral multiple doses of sucralfate prior to partial gastrectomy, and …

Results There was no adverse event with causal relation to superfine dispersed lentinan.
Median survival time was 17.1 months (95% confidence interval: 6.9-25.9 months) in 26 …

To evaluate diagnostic accuracy of endoscopic ultrasonography (EUS) on the extent of
carcinoma of the papilla of Vater, 28 patients were preoperatively evaluated using our EUS …

Omeprazole, a proton pump inhibitor is known to function not only as a proton pump inhibitor
but also as an anti-inflammatory agent, an antioxidant or a stimulator of gastric mucus …