User profiles for RUI-DONG DUAN
Rui-Dong DuanDept of clinical sciences, University of Lund, Sweden Verified email at med.lu.se Cited by 6880 |
Inhibition of cancer cell proliferation in vitro by fruit and berry extracts and correlations with antioxidant levels
The effects of 10 different extracts of fruits and berries on cell proliferation of colon cancer
cells HT29 and breast cancer cells MCF-7 were investigated. The fruits and berries used were …
cells HT29 and breast cancer cells MCF-7 were investigated. The fruits and berries used were …
[HTML][HTML] Absorption and lipoprotein transport of sphingomyelin
Dietary sphingomyelin (SM) is hydrolyzed by intestinal alkaline sphingomyelinase and
neutral ceramidase to sphingosine, which is absorbed and converted to palmitic acid and …
neutral ceramidase to sphingosine, which is absorbed and converted to palmitic acid and …
Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells
…, S Oredsson, V Badmaev, WZ Zhao, RD Duan - …, 2002 - academic.oup.com
Boswellic acids are the effective components of gum resin of Boswellia serrata , which has
anti-inflammatory properties. Recent studies on brain tumors and leukemic cells indicate that …
anti-inflammatory properties. Recent studies on brain tumors and leukemic cells indicate that …
Metabolism of sphingolipids in the gut and its relation to inflammation and cancer development
Sphingolipids are abundant in the microvillar membrane of intestinal epithelial cells where
they are essential for structural integrity and may act as receptors for toxins, virus and bacteria…
they are essential for structural integrity and may act as receptors for toxins, virus and bacteria…
Lycopene suppresses LPS-induced NO and IL-6 production by inhibiting the activation of ERK, p38MAPK, and NF-κB in macrophages
D Feng, WH Ling, RD Duan - Inflammation Research, 2010 - Springer
Background Lycopene has antioxidant, anticancer, and anti-inflammatory effects with
molecular mechanisms not fully identified. Aim and methods We investigated the effects of …
molecular mechanisms not fully identified. Aim and methods We investigated the effects of …
Alkaline sphingomyelinase: an old enzyme with novel implications
RD Duan - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2006 - Elsevier
Alkaline sphingomyelinase (alk-SMase) is present in the intestinal tract and additionally human
bile. It hydrolyses sphingomyelin in both intestinal lumen and the mucosal membrane in …
bile. It hydrolyses sphingomyelin in both intestinal lumen and the mucosal membrane in …
[HTML][HTML] Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family
RD Duan, T Bergman, N Xu, J Wu, Y Cheng… - Journal of Biological …, 2003 - ASBMB
Alkaline sphingomyelinase (alk-SMase) hydrolyzes dietary sphingomyelin and generates
sphingolipid messengers in the gut. In the present study, we purified the enzyme, identified a …
sphingolipid messengers in the gut. In the present study, we purified the enzyme, identified a …
Alkaline sphingomyelinase activity is decreased in human colorectal carcinoma
BACKGROUND The metabolism of sphingomyelin generates important signals regulating
cell proliferation and apoptosis. Previous studies found that the administration of colon …
cell proliferation and apoptosis. Previous studies found that the administration of colon …
[HTML][HTML] Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression
D Feng, L Ohlsson, RD Duan - Lipids in health and disease, 2010 - Springer
Background Curcumin is a polyphenol and the one of the principle curcuminoids of the spice
turmeric. Its antioxidant, anti-cancer and anti-inflammatory effects have been intensively …
turmeric. Its antioxidant, anti-cancer and anti-inflammatory effects have been intensively …
Ursolic acid inhibits proliferation and stimulates apoptosis in HT29 cells following activation of alkaline sphingomyelinase.
BACKGROUND: Ursolic acid (UA) is a plant component with anti-inflammatory and anti-proliferative
properties. Its effect on colon cancer is not clear. We studied the anticancer effects of …
properties. Its effect on colon cancer is not clear. We studied the anticancer effects of …