User profiles for RUI MANUEL REIS

Rui Manuel Reis

Barretos Cancer Hospital (Brazil) and Minho University (Portugal)
Verified email at hcancerbarretos.com.br
Cited by 42778

[HTML][HTML] Frequency of TERT promoter mutations in human cancers

…, F Pardal, JM Lopes, LL Santos, RM Reis… - Nature …, 2013 - nature.com
Reactivation of telomerase has been implicated in human tumorigenesis, but the underlying
mechanisms remain poorly understood. Here we report the presence of recurrent somatic …

Planning cancer control in Latin America and the Caribbean

…, D Sgroi, M Cuello, R Fresco, RM Reis… - The lancet …, 2013 - thelancet.com
Non-communicable diseases, including cancer, are overtaking infectious disease as the
leading health-care threat in middle-income and low-income countries. Latin American and …

[HTML][HTML] Cervical cancer in low and middle‑income countries

…, C Hicks, SM Wang, RM Reis… - Oncology …, 2020 - spandidos-publications.com
Cervical cancer is a malignant tumour that occurs in the cervix and is classified into two
histological types, adenocarcinoma and squamous cell carcinoma (SCC); SCC is more common …

[HTML][HTML] Role of glioblastoma stem cells in cancer therapeutic resistance: A perspective on antineoplastic agents from natural sources and chemical derivatives

…, LS da Silva, AF Evangelista, RM Reis… - Stem Cell Research & …, 2021 - Springer
Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most aggressive
types of cancer, exhibiting rapid cellular growth and highly invasive behavior. Despite …

[HTML][HTML] Serrated pathway in colorectal carcinogenesis

…, C Scapulatempo-Neto, RM Reis… - World journal of …, 2014 - ncbi.nlm.nih.gov
Serrated adenocarcinoma is a recently described subset of colorectal cancer (CRC), which
account for about 10% of all CRCs and follows an alternative pathway in which serrated …

[HTML][HTML] Liquid biopsy for lung cancer: up-to-date and perspectives for screening programs

GMS Casagrande, MO Silva, RM Reis… - International Journal of …, 2023 - mdpi.com
Lung cancer is the deadliest cancer worldwide. Tissue biopsy is currently employed for the
diagnosis and molecular stratification of lung cancer. Liquid biopsy is a minimally invasive …

PD-L1 expression by Tumor Proportion Score (TPS) and Combined Positive Score (CPS) are similar in non-small cell lung cancer (NSCLC)

…, ECA da Silva, VCC de Lima, RM Reis - Journal of Clinical …, 2021 - jcp.bmj.com
Background For non-small cell lung cancer (NSCLC) the most used method for analysing
programmed cell death ligand 1 (PD-L1) expression is the Tumor Proportion Score (TPS). …

[HTML][HTML] Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis

…, GN Berardinelli, A Caetano, RM Reis… - World journal of …, 2018 - ncbi.nlm.nih.gov
AIM To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment
of colonic neoplasms and the expression of inflammatory mediators and microRNAs (…

[HTML][HTML] Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation

…, AF Evangelista, V de Lima Vazquez, RM Reis… - Pharmacological …, 2016 - Elsevier
The BRAF V600E mutation confers constitutive kinase activity and accounts for >90% of
BRAF mutations in melanoma. This genetic alteration is a current therapeutic target; however, …

Screen-printed interdigitated electrodes modified with nanostructured carbon nano-onion films for detecting the cancer biomarker CA19-9

…, ME Melendez, AL Carvalho, RM Reis… - Materials Science and …, 2019 - Elsevier
Nanostructured capacitive biosensors, combined with inexpensive fabrication technologies,
may provide simple, sensitive devices for detecting clinically relevant cancer biomarkers. …