Background The role of bleomycin and dacarbazine in the ABVD regimen (ie, doxorubicin,
bleomycin, vinblastine, and dacarbazine) has been questioned, especially for treatment of …

Purpose: To prove an expected benefit of concurrent radiochemotherapy (RCT), a two-arm
randomized multicentric study was performed. In a subgroup analysis the influence of …

… A part of this work is presented in form of the thesis of Susanne Neumann and Robert Semrau
and was supported partially by grants from the Ministry of Science and Art of Saxony (GHS…

Conclusions. An intensive diagnostic work-up including 18 F-fluorodeoxyglucose positron
emission tomography (FDG-PET) detects many unknown primary tumours, leads to a low …

Background Carcinoma of unknown primary (CUP) of the neck are heterogeneous tumors
in their clinical and biological characteristics, and a preoperative prognostic marker is …

Stereotactic radiosurgery (SRS) is the accurate, conformal delivery of high‐dose radiation to
well‐defined targets while minimizing normal structure doses via steep dose gradients. …

Purpose: Phase II trials in locally advanced rectal cancer have shown that cetuximab-based
neoadjuvant radiochemotherapy is feasible but without an improvement in complete …

Radiotherapy plays an important role in the treatment of head and neck cancer. It represents
the main curative option in advanced tumors. Due to technical progress of treatment …

Purpose To evaluate efficacy and toxicity of stereotactic body radiation therapy (SBRT) with
CyberKnife®(Accuray, Sunnyvale, CA, USA) in a selected cohort of primary, medically …

Background The prognostic effect of neoadjuvant treatment in advanced oesophageal
cancer is still debated because most studies included undefined T-stages, different radio/…