Human protein factory for converting the transcriptome into an in vitro–expressed proteome
…, Y Kawamura, A Fukumoto, A Miura, R Honma… - Nature …, 2008 - nature.com
Appropriate resources and expression technology necessary for human proteomics on a
whole-proteome scale are being developed. We prepared a foundation for simple and efficient …
whole-proteome scale are being developed. We prepared a foundation for simple and efficient …
NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells
…, H Satoh, S Azuma, M Hayashi, K Shimizu, R Honma… - Cancer research, 2008 - AACR
ErbB2-negative breast tumors represent a significant therapeutic hurdle because of a lack
of effective molecular targets. Although NOTCH proteins are known to be involved in …
of effective molecular targets. Although NOTCH proteins are known to be involved in …
Constitutive activation of nuclear factor‐κB is preferentially involved in the proliferation of basal‐like subtype breast cancer cell lines
Constitutive nuclear factor (NF)‐κB activation is thought to be involved in survival, invasion,
and metastasis in various types of cancers. However, neither the subtypes of breast cancer …
and metastasis in various types of cancers. However, neither the subtypes of breast cancer …
[HTML][HTML] FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma
…, E Ito, Y Yanagisawa, R Honma… - International …, 2015 - spandidos-publications.com
Personalized therapy for non‑small cell lung cancer (NSCLC), particularly lung adenocarcinoma,
has recently been significantly improved by the discovery of various molecular targets. …
has recently been significantly improved by the discovery of various molecular targets. …
Influence of inhalation anesthesia assessed by comprehensive gene expression profiling
A Sakamoto, J Imai, A Nishikawa, R Honma, E Ito… - Gene, 2005 - Elsevier
Although general anesthesia is routinely used as an essential surgical procedure and its
harmlessness has been evaluated and endorsed by clinical outcomes, little is known about its …
harmlessness has been evaluated and endorsed by clinical outcomes, little is known about its …
Interaction between polyamines and nucleic acids or phospholipids
…, I Sakamoto, N Goto, K Kashiwagi, R Honma… - Archives of biochemistry …, 1982 - Elsevier
The binding of polyamines to DNA, RNA, and phospholipids has been studied by gel filtration
and sucrose density gradient centrifugation. Spermine was found to bind more to a GC-…
and sucrose density gradient centrifugation. Spermine was found to bind more to a GC-…
FoxA1 as a lineage-specific oncogene in luminal type breast cancer
N Yamaguchi, E Ito, S Azuma, R Honma… - Biochemical and …, 2008 - Elsevier
The forkhead transcription factor FoxA1 is thought to be involved in mammary tumorigenesis.
However, the precise role of FoxA1 in breast cancer development is controversial. We …
However, the precise role of FoxA1 in breast cancer development is controversial. We …
[HTML][HTML] Autocrine and paracrine interactions between multiple myeloma cells and bone marrow stromal cells by growth arrest-specific gene 6 cross-talk with …
…, E Ito, J Imai, Y Yanagisawa, R Honma… - Journal of Biological …, 2017 - ASBMB
The pathogenesis of multiple myeloma (MM) has not yet been fully elucidated. Our microarray
analysis and immunohistochemistry revealed significant up-regulation of growth arrest-…
analysis and immunohistochemistry revealed significant up-regulation of growth arrest-…
A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion protein of …
E Ito, R Honma, J Imai, S Azuma, T Kanno… - The American journal of …, 2003 - Elsevier
Recurrent chromosomal translocations in neoplasms often generate hybrid genes that play
critical roles in tumorigenesis. Desmoplastic small round-cell tumor (DSRCT) is an …
critical roles in tumorigenesis. Desmoplastic small round-cell tumor (DSRCT) is an …
[HTML][HTML] Measles virus induces cell-type specific changes in gene expression
H Sato, R Honma, M Yoneda, R Miura… - Virology, 2008 - Elsevier
Measles virus (MV) causes various responses including the induction of immune responses,
transient immunosuppression and establishment of long-lasting immunity. To obtain a …
transient immunosuppression and establishment of long-lasting immunity. To obtain a …