Human protein factory for converting the transcriptome into an in vitro–expressed proteome

…, Y Kawamura, A Fukumoto, A Miura, R Honma… - Nature …, 2008 - nature.com
Appropriate resources and expression technology necessary for human proteomics on a
whole-proteome scale are being developed. We prepared a foundation for simple and efficient …

NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells

…, H Satoh, S Azuma, M Hayashi, K Shimizu, R Honma… - Cancer research, 2008 - AACR
ErbB2-negative breast tumors represent a significant therapeutic hurdle because of a lack
of effective molecular targets. Although NOTCH proteins are known to be involved in …

Constitutive activation of nuclear factor‐κB is preferentially involved in the proliferation of basal‐like subtype breast cancer cell lines

N Yamaguchi, T Ito, S Azuma, E Ito, R Honma… - Cancer …, 2009 - Wiley Online Library
Constitutive nuclear factor (NF)‐κB activation is thought to be involved in survival, invasion,
and metastasis in various types of cancers. However, neither the subtypes of breast cancer …

[HTML][HTML] FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma

…, E Ito, Y Yanagisawa, R Honma… - International …, 2015 - spandidos-publications.com
Personalized therapy for non‑small cell lung cancer (NSCLC), particularly lung adenocarcinoma,
has recently been significantly improved by the discovery of various molecular targets. …

Influence of inhalation anesthesia assessed by comprehensive gene expression profiling

A Sakamoto, J Imai, A Nishikawa, R Honma, E Ito… - Gene, 2005 - Elsevier
Although general anesthesia is routinely used as an essential surgical procedure and its
harmlessness has been evaluated and endorsed by clinical outcomes, little is known about its …

Interaction between polyamines and nucleic acids or phospholipids

…, I Sakamoto, N Goto, K Kashiwagi, R Honma… - Archives of biochemistry …, 1982 - Elsevier
The binding of polyamines to DNA, RNA, and phospholipids has been studied by gel filtration
and sucrose density gradient centrifugation. Spermine was found to bind more to a GC-…

FoxA1 as a lineage-specific oncogene in luminal type breast cancer

N Yamaguchi, E Ito, S Azuma, R Honma… - Biochemical and …, 2008 - Elsevier
The forkhead transcription factor FoxA1 is thought to be involved in mammary tumorigenesis.
However, the precise role of FoxA1 in breast cancer development is controversial. We …

[HTML][HTML] Autocrine and paracrine interactions between multiple myeloma cells and bone marrow stromal cells by growth arrest-specific gene 6 cross-talk with …

…, E Ito, J Imai, Y Yanagisawa, R Honma… - Journal of Biological …, 2017 - ASBMB
The pathogenesis of multiple myeloma (MM) has not yet been fully elucidated. Our microarray
analysis and immunohistochemistry revealed significant up-regulation of growth arrest-…

A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion protein of …

E Ito, R Honma, J Imai, S Azuma, T Kanno… - The American journal of …, 2003 - Elsevier
Recurrent chromosomal translocations in neoplasms often generate hybrid genes that play
critical roles in tumorigenesis. Desmoplastic small round-cell tumor (DSRCT) is an …

[HTML][HTML] Measles virus induces cell-type specific changes in gene expression

H Sato, R Honma, M Yoneda, R Miura… - Virology, 2008 - Elsevier
Measles virus (MV) causes various responses including the induction of immune responses,
transient immunosuppression and establishment of long-lasting immunity. To obtain a …