[HTML][HTML] α-Pinene: docking study, cytotoxicity, mechanism of action, and anti-biofilm effect against Candida albicans
…, LO e Lima, LA da Silva, MC Fonseca, RC Ferreira… - Antibiotics, 2023 - ncbi.nlm.nih.gov
Candida albicans is associated with serious infections in immunocompromised patients.
Terpenes are natural-product derivatives, widely studied as antifungal alternatives. In a …
Terpenes are natural-product derivatives, widely studied as antifungal alternatives. In a …
[HTML][HTML] A novel piperine analogue exerts in vivo antitumor effect by inducing oxidative, antiangiogenic and immunomodulatory actions
RC Ferreira, TM Batista, SS Duarte, DKF Silva… - Biomedicine & …, 2020 - Elsevier
Structural diversity characterizes natural products as prototypes for design of lead compounds.
The aim of this study was to synthetize, and to evaluate the toxicity and antitumor action of …
The aim of this study was to synthetize, and to evaluate the toxicity and antitumor action of …
[HTML][HTML] α-Pinene: Docking Study, Cytotoxicity, Mechanism of Action, and Anti-Biofilm Effect against Candida albicans
…, L Alves da Silva, M Cavalcante Fonseca, RC Ferreira… - Antibiotics, 2023 - mdpi.com
Candida albicans is associated with serious infections in immunocompromised patients.
Terpenes are natural-product derivatives, widely studied as antifungal alternatives. In a …
Terpenes are natural-product derivatives, widely studied as antifungal alternatives. In a …
Apoptotic and antioxidant effects in HCT-116 colorectal carcinoma cells by a spiro-acridine compound, AMTAC-06
…, CCN de Andrade, VM de Sousa, RC Ferreira… - Pharmacological …, 2022 - Springer
Background Acridine compounds have been described as promising anticancer agents.
Previous studies showed that (E)-1’-((4-chlorobenzylidene)amino)-5’-oxo-1’,5’-dihydro-10H-…
Previous studies showed that (E)-1’-((4-chlorobenzylidene)amino)-5’-oxo-1’,5’-dihydro-10H-…
[HTML][HTML] Chemical Composition, In Vitro Antitumor Effect, and Toxicity in Zebrafish of the Essential Oil from Conyza bonariensis (L.) Cronquist (Asteraceae)
RC Ferreira, YM do Nascimento, PB de Araújo Loureiro… - Biomolecules, 2023 - mdpi.com
The essential oil from Conyza bonariensis (Asteraceae) aerial parts (CBEO) was extracted
by hydrodistillation in a Clevenger-type apparatus and was characterized by gas …
by hydrodistillation in a Clevenger-type apparatus and was characterized by gas …
Cytotoxicity of a new spiro-acridine derivative: Modulation of cellular antioxidant state and induction of cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma
…, SS Duarte, DKF Silva, RC Ferreira… - Naunyn-Schmiedeberg's …, 2024 - Springer
Colorectal cancer (CRC) ranks as the third most common primary malignancy. Epidemiological
data projected approximately 1.9 million new cases and 0.9 million deaths globally in …
data projected approximately 1.9 million new cases and 0.9 million deaths globally in …
Anticancer effect of a spiro-acridine compound involves immunomodulatory and anti-angiogenic actions
…, TÍMH Lisboa, RG Gouveia, RC Ferreira… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Studies with acridine compounds have reported anticancer effects. Herein,
we evaluated the toxicity and antitumor effect of the (E)-1’-((4-chlorobenzylidene)amino)-5’-…
we evaluated the toxicity and antitumor effect of the (E)-1’-((4-chlorobenzylidene)amino)-5’-…
[HTML][HTML] Ionic channels as potential therapeutic targets for erectile dysfunction: a review
AFA Diniz, RC Ferreira, ILL de Souza… - Frontiers in …, 2020 - frontiersin.org
Erectile dysfunction (ED) is a prevalent condition, especially in men over 40 years old,
characterized by the inability to obtain and/or maintain penile erection sufficient for satisfactory …
characterized by the inability to obtain and/or maintain penile erection sufficient for satisfactory …
[HTML][HTML] The Essential Oil from Conyza bonariensis (L.) Cronquist (Asteraceae) Exerts an In Vitro Antimelanoma Effect by Inducing Apoptosis and Modulating the …
RC Ferreira, SS Duarte, VM de Sousa, RRM de Souza… - Pharmaceuticals, 2023 - mdpi.com
The characterization and cytotoxicity of the essential oil from Conyza bonariensis (L.) aerial
parts (CBEO) were previously conducted. The major compound was (Z)-2-lachnophyllum …
parts (CBEO) were previously conducted. The major compound was (Z)-2-lachnophyllum …
Coumarin derivative 7-isopentenyloxycoumarin induces in vivo antitumor activity by inhibit angiogenesis via CCL2 chemokine decrease
…, JAF Dos Santos, RA de Abrantes, RC Ferreira… - Naunyn-Schmiedeberg's …, 2020 - Springer
Cancer is one of the most urgent problems in medicine. In recent years, cancer is the
second leading cause of death globally. In search for more effective and less toxic treatment …
second leading cause of death globally. In search for more effective and less toxic treatment …