User profiles for PITHI CHANVORACHOTE

Pithi Chanvorachote

Associate Professor of Pharmacology, Chulalongkorn University
Verified email at chula.ac.th
Cited by 6731

[HTML][HTML] Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells

…, A Çapci, V Klein, P Chanvorachote… - Cell death & …, 2019 - nature.com
Cancer stem cells (CSCs) residing in colorectal cancer tissues have tumorigenic capacity
and contribute to chemotherapeutic resistance and disease relapse. It is well known that the …

Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways

…, D Phummiratch, K Kulthong, P Chanvorachote… - Toxicology in vitro, 2013 - Elsevier
Silver nanoparticles (AgNPs) are incorporated into a large number of consumer and medical
products. Several experiments have demonstrated that AgNPs can be toxic to the vital …

[HTML][HTML] Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1

…, V Pongrakhananon, L Wang, P Chanvorachote - Journal of Biological …, 2010 - ASBMB
The acquired capability of tumor cells to migrate and invade neighboring tissues is
associated with high metastatic potential and advanced stage of cancers. Recently, signaling …

Long-term cisplatin exposure impairs autophagy and causes cisplatin resistance in human lung cancer cells

…, T Pengsuparp, P Chanvorachote - Molecular and cellular …, 2012 - Springer
Cisplatin-based chemotherapy frequently resulted in acquired resistance of cancer cells.
The underlying mechanism of such resistance is not fully understood especially the …

Lung cancer stem cells and cancer stem cell-targeting natural compounds

…, W Chantarawong, P Chanvorachote - Anticancer …, 2018 - ar.iiarjournals.org
The novel information regarding molecular and translational research have created a paradigm
shift in the understanding of lung cancer biology, revealing the more precise target for …

C-myc contributes to malignancy of lung cancer: a potential anticancer drug target

P Chanvorachote, N Sriratanasak… - Anticancer …, 2020 - ar.iiarjournals.org
Emerging evidence has provided important information on oncoproteins involved in cancer
initiation, progression, metastasis, and resistance to current therapies. C-myc, one of the …

Gigantol, a Bibenzyl from Dendrobium draconis, Inhibits the Migratory Behavior of Non-Small Cell Lung Cancer Cells

S Charoenrungruang, P Chanvorachote… - Journal of Natural …, 2014 - ACS Publications
Lung cancer is one of the most common causes of cancer death due to its high metastasis
potential. The process of cancer migration is an early step that is required for successful …

Integrin as a molecular target for anti-cancer approaches in lung cancer

N Aksorn, P Chanvorachote - Anticancer research, 2019 - ar.iiarjournals.org
Integrins are cell-matrix adhesion molecules providing both mechanical engagement of cell
to extracellular matrix, and generation of cellular signals that are implicated in cancer …

[HTML][HTML] Cytotoxic and Antimigratory Activities of Phenolic Compounds from Dendrobium brymerianum

…, K Busaranon, P Chanvorachote… - Evidence-Based …, 2015 - hindawi.com
Chromatographic separation of a methanol extract prepared from the whole plant of
Dendrobium brymerianum led to the isolation of eight phenolic compounds. Among the isolated …

[HTML][HTML] Gigantol suppresses cancer stem cell-like phenotypes in lung cancer cells

N Bhummaphan, P Chanvorachote - … -Based Complementary and …, 2015 - hindawi.com
As cancer stem cells (CSCs) contribute to malignancy, metastasis, and relapse of cancers,
potential of compound in inhibition of CSCs has garnered most attention in the cancer …