[HTML][HTML] Aging of blood can be tracked by DNA methylation changes at just three CpG sites
Background Human aging is associated with DNA methylation changes at specific sites in
the genome. These epigenetic modifications may be used to track donor age for forensic …
the genome. These epigenetic modifications may be used to track donor age for forensic …
Three decades of data intecration—All problems solved?
P Ziegler, KR Dittrich - Building the Information Society: IFIP 18th World …, 2004 - Springer
Data integration is one of the older research fields in the database area and has merged
shortly after database systems were first introduced into the business world. In this paper, we …
shortly after database systems were first introduced into the business world. In this paper, we …
[PDF][PDF] Humanized mice for modeling human infectious disease: challenges, progress, and outlook
…, C Wang, K Weijer, T Willinger, P Ziegler - Cell host & …, 2009 - cell.com
Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency
virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we …
virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we …
3D co-culture of hematopoietic stem and progenitor cells and mesenchymal stem cells in collagen scaffolds as a model of the hematopoietic niche
Here, we propose a collagen-based three-dimensional (3D) environment for hematopoietic
stem and progenitor cells (HPC) with mesenchymal stem cells (MSC) derived either from …
stem and progenitor cells (HPC) with mesenchymal stem cells (MSC) derived either from …
Data integration—problems, approaches, and perspectives
P Ziegler, KR Dittrich - Conceptual modelling in information systems …, 2007 - Springer
Data integration is one of the older research fields in the database area and has emerged
shortly after database systems were first introduced into the business world. In this paper, we …
shortly after database systems were first introduced into the business world. In this paper, we …
Cutting edge: LPS-induced emergency myelopoiesis depends on TLR4-expressing nonhematopoietic cells
S Boettcher, P Ziegler, MA Schmid… - The Journal of …, 2012 - journals.aai.org
Systemic bacterial infection is rapidly recognized as an emergency state leading to neutrophil
release into the circulation and increased myeloid cell production within the bone marrow. …
release into the circulation and increased myeloid cell production within the bone marrow. …
Pluripotent stem cells escape from senescence-associated DNA methylation changes
Pluripotent stem cells evade replicative senescence, whereas other primary cells lose their
proliferation and differentiation potential after a limited number of cell divisions, and this is …
proliferation and differentiation potential after a limited number of cell divisions, and this is …
[HTML][HTML] Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
New World monkeys of the genus Aotus synthesize a fusion protein (AoT5Cyp) containing
tripartite motif-containing 5 (TRIM5) and cyclophilin A (CypA) that potently blocks HIV-1 …
tripartite motif-containing 5 (TRIM5) and cyclophilin A (CypA) that potently blocks HIV-1 …
[HTML][HTML] Extremely low frequency pulsed electromagnetic fields cause antioxidative defense mechanisms in human osteoblasts via induction of •O2− and H2O2
…, AK Fentz, A Schreiner, J Birk, B Wilbrand, P Ziegler… - Scientific reports, 2017 - nature.com
Recently, we identified a specific extremely low-frequency pulsed electromagnetic field (ELF-PEMF)
that supports human osteoblast (hOBs) function in an ERK1/2-dependent manner, …
that supports human osteoblast (hOBs) function in an ERK1/2-dependent manner, …
Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL–positive leukemias identified by a proteomics approach
S Balabanov, A Gontarewicz, P Ziegler, U Hartmann… - Blood, 2007 - ashpublications.org
Inhibition of BCR-ABL tyrosine kinase with imatinib represents a major breakthrough in the
treatment of patients with chronic myeloid leukemia (CML). However, resistance to imatinib …
treatment of patients with chronic myeloid leukemia (CML). However, resistance to imatinib …