Biomedical applications of nisin
JM Shin, JW Gwak, P Kamarajan… - Journal of applied …, 2016 - academic.oup.com
Nisin is a bacteriocin produced by a group of Gram‐positive bacteria that belongs to
Lactococcus and Streptococcus species. Nisin is classified as a Type A (I) lantibiotic that is …
Lactococcus and Streptococcus species. Nisin is classified as a Type A (I) lantibiotic that is …
Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC 1
NE Joo, K Ritchie, P Kamarajan, D Miao… - Cancer …, 2012 - Wiley Online Library
Nisin, a bacteriocin and commonly used food preservative, may serve as a novel potential
therapeutic for treating head and neck squamous cell carcinoma ( HNSCC ), as it induces …
therapeutic for treating head and neck squamous cell carcinoma ( HNSCC ), as it induces …
Association between metabolic syndrome and periodontitis: The role of lipids, inflammatory cytokines, altered host response, and the microbiome
Periodontitis has been associated with many systemic diseases and conditions, including
metabolic syndrome. Metabolic syndrome is a cluster of conditions that occur concomitantly …
metabolic syndrome. Metabolic syndrome is a cluster of conditions that occur concomitantly …
Sirtuin‐3 (SIRT3), a novel potential therapeutic target for oral cancer
TY Alhazzazi, P Kamarajan, N Joo, JY Huang… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Several sirtuin family members (SIRT1‐7), which are evolutionarily conserved
NAD‐dependent deacetylases, play an important role in carcinogenesis. However, their …
NAD‐dependent deacetylases, play an important role in carcinogenesis. However, their …
[HTML][HTML] SIRT3 and cancer: tumor promoter or suppressor?
TY Alhazzazi, P Kamarajan, E Verdin… - Biochimica et Biophysica …, 2011 - Elsevier
Sirtuins (SIRT1–7), the mammalian homologues of the Sir2 gene in yeast, have emerging
roles in age-related diseases, such as cardiac hypertrophy, diabetes, obesity, and cancer. …
roles in age-related diseases, such as cardiac hypertrophy, diabetes, obesity, and cancer. …
[HTML][HTML] Nisin ZP, a bacteriocin and food preservative, inhibits head and neck cancer tumorigenesis and prolongs survival
P Kamarajan, T Hayami, B Matte, Y Liu, T Danciu… - PloS one, 2015 - journals.plos.org
The use of small antimicrobial peptides or bacteriocins, like nisin, to treat cancer is a new
approach that holds great promise. Nisin exemplifies this new approach because it has been …
approach that holds great promise. Nisin exemplifies this new approach because it has been …
[HTML][HTML] Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a …
Epidemiological studies reveal significant associations between periodontitis and oral cancer.
However, knowledge about the contribution of periodontal pathogens to oral cancer and …
However, knowledge about the contribution of periodontal pathogens to oral cancer and …
Magic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissues
BS Somashekar, P Kamarajan, T Danciu… - Journal of proteome …, 2011 - ACS Publications
High-resolution magic-angle spinning (HR-MAS) proton NMR spectroscopy is used to
explore the metabolic signatures of head and neck squamous cell carcinoma (HNSCC) which …
explore the metabolic signatures of head and neck squamous cell carcinoma (HNSCC) which …
Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target
P Tripathi, P Kamarajan, BS Somashekar… - The international journal …, 2012 - Elsevier
A better understanding of molecular pathways involved in malignant transformation of head
and neck squamous cell carcinoma (HNSCC) is essential for the development of novel and …
and neck squamous cell carcinoma (HNSCC) is essential for the development of novel and …
[HTML][HTML] Microbial Communities Associated with Primary and Metastatic Head and Neck Squamous Cell Carcinoma – A High Fusobacterial and Low Streptococcal …
Given the potential relationship between head and neck squamous cell carcinoma (HNSCC)
and microbial dysbiosis, we profiled the microbiome within healthy normal and tumorous (…
and microbial dysbiosis, we profiled the microbiome within healthy normal and tumorous (…