Clinical utility of biochemical markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines
…, R Lamerz, O Nilsson, C Sturgeon, O Topolcan - European journal of …, 2003 - Elsevier
In recent years, numerous serum and cell/tissue-based markers have been described for
colorectal cancer (CRC). The aim of this article was to provide guidelines for the routine clinical …
colorectal cancer (CRC). The aim of this article was to provide guidelines for the routine clinical …
Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use
…, P Peltomaki, C Sturgeon, O Topolcan - European journal of …, 2007 - Elsevier
The aim of this article is to present updated guidelines for the use of serum, tissue and faecal
markers in colorectal cancer (CRC). Lack of specificity and sensitivity preclude the use of …
markers in colorectal cancer (CRC). Lack of specificity and sensitivity preclude the use of …
[HTML][HTML] Tumor markers in pancreatic cancer: a European Group on Tumor Markers (EGTM) status report
…, VL Holubec, R Klapdor, A Nicolini, O Topolcan… - Annals of oncology, 2010 - Elsevier
Pancreatic ductal adenocarcinoma is one of the most difficult malignancies to diagnose and
treat. The aim of this article is to review how tumor markers can aid the diagnosis and …
treat. The aim of this article is to review how tumor markers can aid the diagnosis and …
Relevance of miR-21 and miR-143 expression in tissue samples of colorectal carcinoma and its liver metastases
V Kulda, M Pesta, O Topolcan, V Liska, V Treska… - Cancer genetics and …, 2010 - Elsevier
MicroRNAs, which are endogenously expressed regulatory noncoding RNAs, have an altered
expression in colorectal cancer. The aim of our study was to assess the relationship of miR…
expression in colorectal cancer. The aim of our study was to assess the relationship of miR…
[PDF][PDF] Tumor markers in staging and prognosis of colorectal carcinoma
M Levy, V Visokai, L Lipska, O Topolcan - Neoplasma, 2008 - researchgate.net
The precise preoperative staging of colorectal cancer is fundamental for surgical strategy,
incomplete staging means incomplete treatment and poor outcome. Large-scale clinical …
incomplete staging means incomplete treatment and poor outcome. Large-scale clinical …
Expression of MMP-7, MMP-9, TIMP-1 and TIMP-2 mRNA in lung tissue of patients with non-small cell lung cancer (NSCLC) and benign pulmonary disease
…, J Dreslerova, J Vrzalova, O Topolcan… - Anticancer …, 2009 - ar.iiarjournals.org
The expression of matrix metallo-proteinases (MMP-7 and MMP-9) and tissue inhibitors of
metalloproteinases (TIMP-1 and TIMP-2), which are involved in the degradation of the …
metalloproteinases (TIMP-1 and TIMP-2), which are involved in the degradation of the …
[HTML][HTML] Prostate cancer management: long-term beliefs, epidemic developments in the early twenty-first century and 3PM dimensional solutions
In the early twenty-first century, societies around the world are facing the paradoxal
epidemic development of PCa as a non-communicable disease. PCa is the most frequently …
epidemic development of PCa as a non-communicable disease. PCa is the most frequently …
[HTML][HTML] Insufficient response to mRNA SARS-CoV-2 vaccine and high incidence of severe COVID-19 in kidney transplant recipients during pandemic
…, P Drenko, L Kielberger, J Machova, O Topolcan… - American Journal of …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination may
fail to sufficiently protect transplant recipients against coronavirus disease 2019 (COVID-19). …
fail to sufficiently protect transplant recipients against coronavirus disease 2019 (COVID-19). …
The role of thymidine kinase in cancer diseases
O Topolcan, L Holubec Jr - Expert opinion on medical diagnostics, 2008 - Taylor & Francis
… The results herein are in accordance with the publications of O'Neill et al. Citation[49]. He …
O Topolcan was supported by the research project VZ MSM 0021620819 and L Holubec …
O Topolcan was supported by the research project VZ MSM 0021620819 and L Holubec …
Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes
…, M Pesta, P Pitule, O Topolcan… - … journal of cancer, 2019 - Wiley Online Library
The natural behavior of mesenchymal stem cells (MSCs) and their exosomes in targeting
tumors is a promising approach for curative therapy. Human tumor tropic mesenchymal stem …
tumors is a promising approach for curative therapy. Human tumor tropic mesenchymal stem …