C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe

…, N Amornwichet, Y Saitoh, K Torikai, N Kubo… - Radiotherapy and …, 2014 - Elsevier
Background and purpose Chromatin remodeling through histone modifications, including
acetylation, plays an important role in the appropriate response to DNA damage induced by …

[HTML][HTML] Moderately hypofractionated carbon ion radiotherapy for prostate cancer; a prospective observational study “GUNMA0702”

H Kawamura, N Kubo, H Sato, T Mizukami, H Katoh… - BMC cancer, 2020 - Springer
Background Carbon ion Radiotherapy for prostate cancer is widely used, however reports
are limited from single institute or short follow up. We performed a prospective observational …

Dosimetric comparison of carbon ion and X-ray radiotherapy for Stage IIIA non–small cell lung cancer

N Kubo, J Saitoh, H Shimada, K Shirai… - Journal of Radiation …, 2016 - academic.oup.com
The present study compared the dose–volume histograms of patients with Stage IIIA non–small
cell lung cancer (NSCLC) treated with carbon ion radiotherapy with those of patients …

[HTML][HTML] Efficacy and safety of carbon-ion radiotherapy for stage I non-small cell lung cancer with coexisting interstitial lung disease

N Okano, N Kubo, K Yamaguchi, S Kouno, Y Miyasaka… - Cancers, 2021 - mdpi.com
Simple Summary Interstitial lung disease (ILD) is a risk factor for lung cancer, but the treatment
options are often limited because of concerns that ILD may worsen with treatment. In this …

[HTML][HTML] Comparison of oncologic outcomes between carbon ion radiotherapy and stereotactic body radiotherapy for early-stage non-small cell lung cancer

Y Miyasaka, S Komatsu, T Abe, N Kubo, N Okano… - Cancers, 2021 - mdpi.com
Simple Summary Lung cancer is a leading cause of cancer-related death. Stereotactic body
radiotherapy (SBRT) is the standard treatment for inoperable early-stage non-small cell lung …

Carbon-ion radiotherapy for inoperable head and neck bone and soft-tissue sarcoma: prospective observational study

A Musha, N Kubo, H Kawamura, N Okano… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Bone and soft-tissue sarcomas of the head and neck have very poor
prognoses. This prospective study aimed to investigate the efficacy and safety of carbon-ion …

Radiosensitizing effect of carboplatin and paclitaxel to carbon-ion beam irradiation in the non-small-cell lung cancer cell line H460

N Kubo, S Noda, A Takahashi, Y Yoshida… - Journal of radiation …, 2015 - academic.oup.com
The present study investigated the ability of carboplatin and paclitaxel to sensitize human
non-small-cell lung cancer (NSCLC) cells to carbon-ion beam irradiation. NSCLC H460 cells …

Clinical results of carbon-ion radiotherapy for stage I non-small cell lung cancer with concomitant interstitial lung disease: a Japanese national registry study (J-CROS …

…, M Nakajima, S Tokumaru, N Kubo… - Journal of Radiation …, 2023 - academic.oup.com
Anti-cancer treatments for lung cancer patients with interstitial lung disease (ILD) are
challenging. The treatment options for ILD are often limited because of concerns that treatments …

[HTML][HTML] Clinical features and dosimetric evaluation of carbon ion radiation-induced osteoradionecrosis of mandible in head and neck tumors

A Musha, H Shimada, N Kubo, H Kawamura… - Radiotherapy and …, 2021 - Elsevier
Background and purpose Osteoradionecrosis (ORN) affects the patient’s quality of life by
making eating and maintaining oral hygiene painful. This study aimed to analyze carbon ion …

[HTML][HTML] A promising treatment strategy for lung cancer: a combination of radiotherapy and immunotherapy

Y Miyasaka, H Sato, N Okano, N Kubo, H Kawamura… - Cancers, 2021 - mdpi.com
Simple Summary Lung cancer is a leading cause of cancer-related deaths worldwide. In the
past few decades, radiotherapy has achieved outstanding technical advances and is widely …