Immunotherapy is a promising area of therapy in patients with neuro-oncological malignancies.
However, early-phase studies show unique challenges associated with the assessment …

Background Patients with incomplete surgical resection of medulloblastoma are controversially
regarded as having a marker of high-risk disease, which leads to patients undergoing …

The fiber-tracking method enables in vivo visualization of the white matter tracts of the brain
using a diffusion tensor MR imaging technique. While this method represents a promising …

The prognostic impact of TERT mutations has been controversial in IDH-wild tumors, particularly
in glioblastomas (GBM). The controversy may be attributable to presence of potential …

Object The object of this study was to investigate the safety and clinical responses of
immunotherapy targeting the WT1 (Wilms tumor 1) gene product in patients with recurrent …

A noninvasive technique for assessing tumor tissue characteristics is required to assist
preoperative surgical planning for malignant brain tumors. Preoperative information on tumor cell …

Object Due to advances in neuroimaging and the increasing use of imaging to screen for brain
disease (“brain checkups”), meningiomas are now often detected as an incidental finding. …

Purpose Whereas whole-brain radiotherapy (WBRT) has been the standard treatment of
brain metastases (BMs), stereotactic radiosurgery (SRS) is increasingly preferred to avoid …

Object The precise natural history of incidentally discovered meningiomas (IDMs) remains
unknown. It has been reported that for symptomatic meningiomas, tumor location can be used …

The open reading frame alr1585 of Anabaena sp. strain PCC 7120 encodes a heme-dependent
peroxidase (Anabaena peroxidase [AnaPX]) belonging to the novel DyP-type …