[HTML][HTML] A novel human serum lectin with collagen-and fibrinogen-like domains that functions as an opsonin

…, S Taira, Y Sato, T Fujita, N Ichikawa, M Nakata… - Journal of Biological …, 1996 - ASBMB
Collectins are C-type animal lectins with both collagenous and carbohydrate recognition
domains and are involved in the first line host defense against pathogens. We report here a …

Human M-ficolin is a secretory protein that activates the lectin complement pathway

Y Liu, Y Endo, D Iwaki, M Nakata… - The Journal of …, 2005 - journals.aai.org
Three types of ficolins have been identified in humans: L-ficolin, M-ficolin, and H-ficolin.
Similar to mannose-binding lectin, L-ficolin and H-ficolin are the recognition molecules in the …

Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans Cantor

…, A Li, Y Inagaki, N Kokudo, S Tamura, M Nakata… - International …, 2011 - Elsevier
The skin of the toad Bufo bufo gargarizans Cantor is known to be rich in bufadienolides,
peptides and alkaloids. It has been found to be a source of some extracts and biologically active …

Cinobufacini, an aqueous extract from Bufo bufo gargarizans Cantor, induces apoptosis through a mitochondria-mediated pathway in human hepatocellular …

…, D Wang, X Cui, B Gao, N Kokudo, M Nakata… - Journal of …, 2010 - Elsevier
AIM OF THE STUDY: Cinobufacini (Huachansu), an aqueous extract from the skin and parotid
venom glands of Bufo bufo gargarizans Cantor, is a traditional Chinese medicine widely …

Origin of the classical complement pathway: Lamprey orthologue of mammalian C1q acts as a lectin

…, A Matsushita, Y Endo, M Nakata… - Proceedings of the …, 2004 - National Acad Sciences
The lectin complement pathway in innate immunity is closely related to the classical
complement pathway in adaptive immunity, with respect to the structures and functions of their …

Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils.

D Campanelli, M Melchior, Y Fu, M Nakata… - The Journal of …, 1990 - rupress.org
Closely similar but nonidentical NH2-terminal amino acid sequences have been reported
for a protein or proteins in human neutrophils whose bioactivities is/are diverse (as a serine …

Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions

…, F Nimmerjahn, JI Furukawa, M Nakata… - The Journal of …, 2008 - journals.aai.org
Replacement of aspartic acid by alanine at position 265 (D265A) in mouse IgG1 results in a
complete loss of interaction between this isotype and low-affinity IgG Fc receptors (FcγRIIB …

Structural changes in the oligosaccharide moiety of human IgG with aging

…, T Yasuda, F Takeuchi, T Konishi, M Nakata… - Glycoconjugate …, 1998 - Springer
In order to elucidate the relationship between glycosylation of IgG and aging, oligosaccharide
structures of human IgG purified from sera of men and women aged 18 to 73 years were …

Curcumin inhibits telomerase activity in human cancer cell lines

…, XJ Qu, YY Xie, L Zhou, M Nakata… - International …, 2006 - spandidos-publications.com
Curcumin, one of the major components of tumeric, the dried rhizome of Curcuma longa L,
has been shown to have anti-proliferating and anti-carcinogenic properties. In this study, we …

An ancient lectin-dependent complement system in an ascidian: novel lectin isolated from the plasma of the solitary ascidian, Halocynthia roretzi

…, R Kasukawa, N Ichikawa, M Nakata… - The Journal of …, 2001 - journals.aai.org
Mannose-binding lectin (MBL) is a C-type lectin involved in the first line of host defense
against pathogens and it requires MBL-associated serine protease (MASP) for activation of the …