Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells

M Suenaga, H Soda, M Oka… - … journal of cancer, 2002 - Wiley Online Library
Telomerase activity is involved in cellular immortality. We have recently demonstrated that
telomerase activity is closely associated with cell proliferation in prostate cancers. Telomerase …

Antiproliferative effects of the histone deacetylase inhibitor FR901228 on small‐cell lung cancer lines and drug‐resistant sublines

J Tsurutani, H Soda, M Oka, M Suenaga… - … journal of cancer, 2003 - Wiley Online Library
FR901228 is a novel histone deacetylase (HDAC) inhibitor, and its antiproliferative effects
on non‐small cell lung cancer cells have been shown in vitro. However, there have been no …

[HTML][HTML] Repeated waon therapy improves pulmonary hypertension during exercise in patients with severe chronic obstructive pulmonary disease

M Umehara, A Yamaguchi, S Itakura, M Suenaga… - Journal of …, 2008 - Elsevier
OBJECTIVES: Repeated Waon therapy, which uses a far infrared-ray dry sauna system,
improved the vascular endothelial function and the cardiac function in patients with chronic …

Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells

…, K Tsukamoto, Y Noguchi, M Suenaga… - Antimicrobial agents …, 2000 - Am Soc Microbiol
To investigate interactions between the multidrug resistance protein (MRP) and antimicrobial
agents, we examined the effects of 12 agents on vincristine sensitivity and efflux of the …

Antiproliferative effects of gefitinib are associated with suppression of E2F-1 expression and telomerase activity

M Suenaga, A Yamaguchi, H Soda, K Orihara… - Anticancer …, 2006 - ar.iiarjournals.org
Background: Gefitinib (Iressa, ZD1839) is a selective epidermal growth factor receptor
tyrosine kinase inhibitor. E2F-1 is a critical determinant in cell cycle. Growth signals up-regulate …

Phase I study of second-line chemotherapy with docetaxel and carboplatin in advanced non-small-cell lung cancer

…, H Soda, S Doi, F Narasaki, M Suenaga… - Cancer chemotherapy …, 2001 - Springer
Purpose: Docetaxel and carboplatin have a broad spectrum of antitumor activity. We conducted
a phase I study of docetaxel and carboplatin as second-line chemotherapy in previously …

Influence of gefitinib and erlotinib on apoptosis and C-MYC expression in H23 lung cancer cells

M Suenaga, M Yamamoto, S Tabata… - Anticancer …, 2013 - ar.iiarjournals.org
Background: Gefitinib and erlotinib are inhibitors of epidermal growth factor receptor tyrosine
kinase. The effects of these tyrosine kinase inhibitors on RAS-mutated cancer cells are …

True malignant histiocytosis with trisomy 9 following primary mediastinal germ cell tumor

M Suenaga, K Matsushita, N Kawamata, T Kukita… - Acta …, 2006 - karger.com
A 24-year-old Japanese man was admitted due to bloody phlegm in May 2002. A diagnosis
of mediastinal germ cell tumor, mixed type involving seminoma, immature teratoma and …

Birth Cohort Effects on Incidence of Lung Cancers: A Population‐based Study in Nagasaki, Japan

…, K Nakatomi, S Kawabata, M Suenaga… - Japanese journal of …, 2000 - Wiley Online Library
Smoking prevalence remains high (around 60%) among Japanese males, but smoking
initiation among males born in the 1930s decreased by approximately 10% due to economic …

Opengate on OpenFlow: system outline

M Suenaga, M Otani, H Tanaka… - 2012 Fourth …, 2012 - ieeexplore.ieee.org
Open gate is a user authentication gateway system for network in the environment opened
to public. This system has been operating for controlling the campus-wide open network in …