[HTML][HTML] Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer

M Sopo, M Anttila, K Hämäläinen, A Kivelä… - BMC cancer, 2019 - Springer
Background In many malignancies including ovarian cancer, different angiogenic factors
have been related to poor prognosis. However, data on their relations to each other or …

[HTML][HTML] High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

M Sopo, H Sallinen, K Hämäläinen, A Kivelä… - PLoS …, 2020 - journals.plos.org
Background Antiangiogenic therapy, although part of standard treatment in ovarian cancer,
has variable efficacy. Furthermore, little is known about the prognostic biomarkers and …

Microvessels in epithelial ovarian tumors: high microvessel density is a significant feature of malignant ovarian tumors

M Sopo, M Anttila, OT Muukkonen… - Anticancer …, 2020 - ar.iiarjournals.org
Background/Aim: Examine features of blood and lymphatic vessels in ovarian tumors and
their significance to prognosis of ovarian cancer. Patients and Methods: A total of 139 women …

Antiangiogenic gene therapy with soluble VEGF‐receptors‐1,‐2 and‐3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma

M Sopo, M Anttila, H Sallinen… - … journal of cancer, 2012 - Wiley Online Library
We compared effects of antiangiogenic gene therapy with a combination of soluble sVEGFR‐1,
sVEGFR‐2 and sVEGFR‐3 to chemotherapy with carboplatin and paclitaxel and to …

[PDF][PDF] Epithelial ovarian cancer and angiogenesis: biomarker and gene therapy study

M Sopo - 2021 - erepo.uef.fi
Sopo, Minna Epithelial ovarian cancer and angiogenesis, Biomarker and gene therapy study
… I also wish to thank my parents-in-law Pirkko and Raimo Sopo for helping our family during …

[HTML][HTML] The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

H Yu, S Zhang, R Zhang, L Zhang - Journal of Experimental & Clinical …, 2009 - Springer
Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and
their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma. …

[HTML][HTML] Fibulin-4 is associated with tumor progression and a poor prognosis in ovarian carcinomas

J Chen, Z Liu, S Fang, R Fang, X Liu, Y Zhao, XX Li… - BMC cancer, 2015 - Springer
Background Fibulin-4, a member of the fibulin family of extracellular glycoproteins, is
implicated in the progressions of some cancers. However, no information has been available to …

[PDF][PDF] Responses in biomarkers of arterial function, inflammation, and appetite regulation during a long agonist in vitro fertilization protocol

J Leppänen - 2022 - erepo.uef.fi
During a long agonist in vitro fertilization (IVF) protocol broad hormonal changes occur. This
protocol usually lasts from three to four weeks altogether. First, estrogen levels are deficient …

[PDF][PDF] Ovarian cancer and gene therapy-modelling, angiogenesis and targeting vascular supply

H Sallinen - 2010 - erepo.uef.fi
Ovarian cancer is the most lethal of all gynaecological malignancies. Despite current treatment
approaches, surgery and chemotherapy, the prognosis still remains poor. Therefore, new …

[HTML][HTML] VEGF-c expression in an in vivo model of orthotopic endometrial cancer and retroperitoneal lymph node metastasis

YW Huang, LQ Xu, RZ Luo, X Huang, T Hou… - Reproductive Biology …, 2013 - Springer
Background Retroperitoneal lymph node (RLN) metastasis is an important indicator of
endometrial cancer (EC) prognosis. Because vascular endothelial growth factor c (VEGF-c) is …