Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

…, K Khetchoumian, M Ignat… - Proceedings of the …, 2011 - National Acad Sciences
TRIM24 (TIF1α), TRIM28 (TIF1β), and TRIM33 (TIF1γ) are three related cofactors belonging
to the tripartite motif superfamily that interact with distinct transcription factors. TRIM24 …

Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha

…, M Teletin, J Tisserand, M Mark, B Herquel, M Ignat… - Nature …, 2007 - nature.com
Hepatocellular carcinoma (HCC) is a major cause of death worldwide. Here, we provide
evidence that the ligand-dependent nuclear receptor co-regulator Trim24 (also known as Tif1α) …

Small bowel ischemia and SARS-CoV-2 infection: an underdiagnosed distinct clinical entity

M Ignat, G Philouze, L Aussenac-Belle, V Faucher… - Surgery, 2020 - Elsevier
Gastrointestinal symptoms have been described in up to 39% of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infected patients. 1 Evidence for SARS-CoV-2 …

[HTML][HTML] 18F-Fluorocholine PET and Multiphase CT Integrated in Dual Modality PET/4D-CT for Preoperative Evaluation of Primary Hyperparathyroidism

V Pretet, M Rotania, M Helali, M Ignat, M Vix… - Journal of Clinical …, 2020 - mdpi.com
The present retrospective study evaluates the diagnostic value of integrated 18 F-Fluorocholine
positron emission tomography/four-dimensional contrast-enhanced computed …

[HTML][HTML] 18F-Fluorocholine PET and 4D-CT in Patients with Persistent and Recurrent Primary Hyperparathyroidism

A Latge, S Riehm, M Vix, J Bani, M Ignat, V Pretet… - Diagnostics, 2021 - mdpi.com
Patients with primary hyperparathyroidism (pHPT) can develop persistent (P-pHPT) or
recurrent (R-pHPT) disease after parathyroidectomy. Before recommending reoperation, …

Indications and long-term outcomes of conversion of sleeve gastrectomy to Roux-en-Y gastric bypass

A D'Urso, M Vix, S Perretta, M Ignat, L Scheer, D Mutter - Obesity surgery, 2021 - Springer
Purpose Long-term results on sleeve gastrectomy (SG) with more than 10 years report
patients needing sleeve revision for weight loss failure, de novo gastroesophageal reflux (GERD), …

[HTML][HTML] Multimodal imaging of a humanized orthotopic model of hepatocellular carcinoma in immunodeficient mice

T Wu, E Heuillard, V Lindner, G Bou About, M Ignat… - Scientific reports, 2016 - nature.com
The development of multimodal strategies for the treatment of hepatocellular carcinoma
requires tractable animal models allowing for advanced in vivo imaging. Here, we characterize …

A cost analysis of healthcare episodes including day-case bariatric surgery (Roux-en-Y gastric bypass and sleeve gastrectomy) versus inpatient surgery

M Ignat, J Ansiaux, S Osailan, A D'Urso… - Obesity Surgery, 2022 - Springer
Background Assessing the medico-economic outcomes of a healthcare pathway including
day-case bariatric surgery versus the conventional pathway. Methods This economical …

Pharmacological enhancement of autophagy induced in a hepatocellular carcinoma cell line by high-LET radiation

A Altmeyer, AC Jung, M Ignat, S Benzina… - Anticancer …, 2010 - ar.iiarjournals.org
The aim of the present study was to determine the cytotoxic consequences of high-linear
energy transfer (LET) irradiation in the presence of oxaliplatin on hepatocellular carcinoma (…

Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1α

M Ignat, M Teletin, J Tisserand… - Proceedings of the …, 2008 - National Acad Sciences
Calcification of arteries is a major risk factor for cardiovascular mortality in humans. Using
genetic approaches, we demonstrate here that the transcriptional intermediary factor 1α (TIF1α)…