Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

Background: Data for multiple common susceptibility alleles for breast cancer may be combined
to identify women at different levels of breast cancer risk. Such stratification could guide …

Objective: To investigate whether the nature of the relationship between body mass index (BMI
(kg/m 2)) and all-cause mortality is direct, J-or U-shaped, and whether this relationship …

We studied cancer mortality in a cohort of 5,573 women with scoliosis and other spine disorders
who were diagnosed between 1912 and 1965 and were exposed to frequent diagnostic …

Background: Ionizing radiation is a well-established human mammary carcinogen. Women
historically monitored by radiography at young ages for abnormal spinal curvature are an …

Background While tobacco and alcohol are established risk factors for hepatocellular carcinoma
(HCC), the most common type of primary liver cancer, it is unknown whether they also …

Various common genetic susceptibility loci have been identified for breast cancer; however,
it is unclear how they combine with lifestyle/environmental risk factors to influence risk. We …

OBJECTIVE. The purpose of this study was to examine risks of cancer incidence and mortality
among US radiation technologists performing or assisting with fluoroscopically guided …

Importance Radioactive iodine (RAI) has been used extensively to treat hyperthyroidism
since the 1940s. Although widely considered a safe and effective therapy, RAI has been …

BACKGROUND: Both smoking and obesity have been linked to increased mortality, but
evaluating the joint effect has been limited. This nationwide, prospective mortality study of US …