Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

Background The pathological complete response (pCR) after neoadjuvant chemotherapy is
a surrogate marker for a favorable prognosis in breast cancer patients. Factors capable of …

BACKGROUND. It is believed widely that chemotherapy‐induced cognitive impairment occurs
in a subgroup of patients with breast cancer. However, recent reports have provided no …

Breast cancer is the most common cancer among women. To date, 22 common breast cancer
susceptibility loci have been identified accounting for ∼8% of the heritability of the disease…

Introduction MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA molecules
with relevance as regulators of gene expression thereby affecting crucial processes in cancer …

Breast cancer (BC) is the most frequent carcinoma in women. The cumulative risk for the
disease is 10% up to the age of 80 years. A familial history of BC and ovarian cancer (OC) is a …

The breast cancer risk variants identified in genome-wide association studies explain only a
small fraction of the familial relative risk, and the genes responsible for these associations …

Triple-negative (TN) breast cancer is an aggressive subtype of breast cancer associated with
a unique set of epidemiologic and genetic risk factors. We conducted a two-stage genome-…

Background: Increasing effort has been put in the implementation and certification of breast
centers in order to establish standardized, quality assured health care for breast cancer …

INTRODUCTION: The proliferation biomarker Ki-67 is a prognostic factor for breast cancer
that has been investigated in several retrospective studies and a few prospective ones. The …