Hereditary breast and ovarian cancer: review and future perspectives

MP Lux, PA Fasching, MW Beckmann - Journal of molecular medicine, 2006 - Springer
Breast cancer (BC) is the most frequent carcinoma in women. The cumulative risk for the
disease is 10% up to the age of 80 years. A familial history of BC and ovarian cancer (OC) is a …

[HTML][HTML] The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

…, T Jaeger, F Landauer, G Lindl, M Lux… - British journal of …, 2018 - Elsevier
Background The surgical safety checklist is widely used to improve the quality of perioperative
care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods …

AGO recommendations for the diagnosis and treatment of patients with early breast cancer: update 2022

…, C Kolberg-Liedtke, S Loibl, D Lüftner, MP Lux… - Breast Care, 2022 - karger.com
Introduction: The AGO (Arbeitsgemeinschaft Gynäkologische Onkologie, German Gynecological
Oncology Group) Task Force on Diagnosis and Treatment of Breast Cancer as an …

[PDF][PDF] Polygenic risk scores for prediction of breast cancer and breast cancer subtypes

…, WY Lo, S Loibl, J Long, J Lubiński, MP Lux… - The American Journal of …, 2019 - cell.com
Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

Cognitive function during neoadjuvant chemotherapy for breast cancer: results of a prospective, multicenter, longitudinal study

K Hermelink, M Untch, MP Lux, R Kreienberg, T Beck… - Cancer, 2007 - Wiley Online Library
BACKGROUND. It is believed widely that chemotherapy‐induced cognitive impairment occurs
in a subgroup of patients with breast cancer. However, recent reports have provided no …

[HTML][HTML] Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment

…, MR Bani, M Schrauder, L Kahmann, MP Lux… - BMC cancer, 2011 - Springer
Background The pathological complete response (pCR) after neoadjuvant chemotherapy is
a surrogate marker for a favorable prognosis in breast cancer patients. Factors capable of …

[HTML][HTML] Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection

…, PL Strissel, L Kahmann, CR Loehberg, MP Lux… - PloS one, 2012 - journals.plos.org
Introduction MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA molecules
with relevance as regulators of gene expression thereby affecting crucial processes in cancer …

Genome-wide association analysis identifies three new breast cancer susceptibility loci

…, S Verhoef, FBL Hogervorst, PA Fasching, MP Lux… - Nature …, 2012 - nature.com
Breast cancer is the most common cancer among women. To date, 22 common breast cancer
susceptibility loci have been identified accounting for ∼8% of the heritability of the disease…

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

…, WY Lo, S Loibl, J Lubinski, C Luccarini, MP Lux… - Nature …, 2018 - nature.com
The breast cancer risk variants identified in genome-wide association studies explain only a
small fraction of the familial relative risk, and the genes responsible for these associations …

Two different sides of 'chemobrain': determinants and nondeterminants of self‐perceived cognitive dysfunction in a prospective, randomized, multicenter study

…, H Küchenhoff, M Untch, I Bauerfeind, MP Lux… - Psycho …, 2010 - Wiley Online Library
Objective: Complaints of cognitive dysfunction are frequent among cancer patients. Many
studies have identified neuropsychological compromise associated with cancer and cancer …