Context: Bisphenol A (BPA) is a widespread industrial compound used in the synthesis of
polycarbonate plastics. In experimental animals, neonatal exposure to BPA results in a …

Muscle injury induces strong changes in muscle cells and extracellular matrix. Muscle
regeneration after injury has similarities to muscle development during embryogenesis and seems …

IGF-1 is a potent mitogen of major importance in the mammary gland. IGF-1 binding to the
cognate receptor, IGF-1R, triggers a signaling cascade leading to proliferative and anti-…

Circadian rhythms show universally a 24-h oscillation pattern in metabolic, physiological and
behavioral functions of almost all species. This pattern is due to a fundamental adaptation …

The human insulin-like growth factor-1 (IGF-1) gene gives rise to multiple, heterogeneous
mRNA transcripts through a combination of multiple transcription initiation sites, alternative …

Both type I and II interferons (IFNs) have been implicated in the pathogenesis of Sjogren's
syndrome (SS). We aimed to explore the contribution of type I and II IFN signatures in the …

Colorectal cancer (CRC) is one of the most commonly diagnosed and lethal cancers worldwide.
It is a multistep process that requires the accumulation of genetic/epigenetic aberrations. …

The serine / threonine kinase Akt functions intracellularly as a cardinal nodal point for a
constellation of converging upstream signaling pathways, which involve stimulation of receptor …

OBJECTIVE Fat distribution is an important variable explaining metabolic heterogeneity of
obesity. Abdominal subcutaneous adipose tissue (SAT) is divided by the Scarpa’s fascia into …

In recent years, cellular senescence has generated a lot of interest among researchers
because of its involvement in both the normal aging process and common human diseases. …