Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre

…, S Klenow, C Miene, U Munjal, K Stein, M Glei - … Research/Reviews in …, 2009 - Elsevier
Dietary fibres are indigestible food ingredients that reach the colon and are then fermented
by colonic bacteria, resulting mainly in the formation of short-chain fatty acids (SCFA) such as …

[HTML][HTML] Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African …

V Mai, QM McCrary, R Sinha, M Glei - Nutrition journal, 2009 - Springer
Background African Americans (AA) suffer from an increased incidence and mortality of
colorectal cancer (CRC). Environmental exposures including dietary habits likely contribute to a …

Isoflavonoids and lignans have different potentials to modulate oxidative genetic damage in human colon cells

BL Pool-Zobel, H Adlercreutz, M Glei… - …, 2000 - academic.oup.com
Polyphenolic compounds, including isoflavonoids and lignans, have been suggested to be
chemopreventive on account of antioxidative properties. In this context it is of importance to …

Iron-overload induces oxidative DNA damage in the human colon carcinoma cell line HT29 clone 19A

M Glei, GO Latunde-Dada, A Klinder, TW Becker… - … /Genetic Toxicology and …, 2002 - Elsevier
Dietary iron may contribute to colon cancer risk via production of reactive oxygen species (ROS).
The aim of the study was to determine whether physiological ferric/ferrous iron induces …

B-vitamins, carotenoids and α-/γ-tocopherol in raw and roasted nuts

W Stuetz, W Schlörmann, M Glei - Food chemistry, 2017 - Elsevier
The concentrations of B-vitamins, carotenoids and tocopherols in nuts may differ between
species and might be influenced by roasting. Thiamine, riboflavin, pyridoxine, lutein, …

Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes

M Glei, S Klenow, J Sauer, U Wegewitz… - Mutation Research …, 2006 - Elsevier
Epidemiological findings have indicated that red meat increases the likelihood of colorectal
cancer. Aim of this study was to investigate whether hemoglobin, or its prosthetic group heme…

Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources

G Beyer-Sehlmeyer, M Glei, E Hartmann… - British journal of …, 2003 - cambridge.org
Dietary fibre sources are fermented by the gut flora to yield short-chain fatty acids (SCFA)
together with degraded phytochemicals and plant nutrients. Butyrate, a major SCFA, is …

Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress

…, S Vertuani, S Manfredini, D Scharlau, M Glei… - Free Radical Biology …, 2010 - Elsevier
Although the metabolism of vitamin E has been extensively studied in cell culture, animals,
and humans, biochemical analyses of intermediate metabolites are scarce. We here describe …

First molecular cytogenetic high resolution characterization of the NIH 3T3 cell line by murine multicolor banding

…, N Kosyakova, H Mkrtchyan, M Glei… - … of Histochemistry & …, 2013 - journals.sagepub.com
Since being established in 1963, the murine fibroblast cell line NIH 3T3 has been used in
thousands of studies. NIH 3T3 immortalized spontaneously and became tetraploid shortly after …

Bread enriched with green coffee extract has chemoprotective and antigenotoxic activities in human cells

M Glei, A Kirmse, N Habermann, C Persin… - Nutrition and …, 2006 - Taylor & Francis
Recent studies have shown that bread supplemented with functional ingredients was more
chemoprotective than nonsupplemented bread. Here we investigated components of a …