User profiles for MICHAEL A. GROTZER
Michael GrotzerProfessor of Pediatrics, University Children's Hospital of Zurich Verified email at kispi.uzh.ch Cited by 13112 |
Resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
A Eggert, MA Grotzer, TJ Zuzak, BR Wiewrodt, R Ho… - Cancer research, 2001 - AACR
Disruption of apoptotic pathways may be involved in tumor formation,regression, and
treatment resistance of neuroblastoma (NB). Tumor necrosis factor-related apoptosis-inducing …
treatment resistance of neuroblastoma (NB). Tumor necrosis factor-related apoptosis-inducing …
Outcome of craniopharyngioma in children: long-term complications and quality of life
Childhood craniopharyngiomas are histologically benign tumours arising from remnants of
Rathke's pouch in the hypothalamic–pituitary region. The two common treatment approaches …
Rathke's pouch in the hypothalamic–pituitary region. The two common treatment approaches …
[HTML][HTML] Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the …
Purpose Diffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median
survival of< 1 year. The International and European Society for Pediatric Oncology DIPG …
survival of< 1 year. The International and European Society for Pediatric Oncology DIPG …
[HTML][HTML] Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
…, M Perez-Somarriba, CC Faria, MA Grotzer… - Nature …, 2019 - nature.com
Infant gliomas have paradoxical clinical behavior compared to those in children and adults:
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …
Delay in the diagnosis of paediatric brain tumours
…, H Hengartner, E Boltshauser, MA Grotzer - European journal of …, 2002 - Springer
The pre-diagnostic period of 252 children (median age 6.3 years, range 0–16.9 years) with
primary brain tumours was assessed to analyse their clinical presentation and reasons for …
primary brain tumours was assessed to analyse their clinical presentation and reasons for …
[HTML][HTML] Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
…, M Perez-Somarriba, CC Faria, MA Grotzer… - Nature …, 2019 - ncbi.nlm.nih.gov
Infant gliomas have paradoxical clinical behavior compared to those in children and adults:
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …
low-grade tumors have a higher mortality rate, while high-grade tumors have a better …
Background ionizing radiation and the risk of childhood cancer: a census-based nationwide cohort study
…, M Röösli, F Niggli, MA Grotzer… - Environmental …, 2015 - ehp.niehs.nih.gov
Background Exposure to medium or high doses of ionizing radiation is a known risk factor for
cancer in children. The extent to which low-dose radiation from natural sources contributes …
cancer in children. The extent to which low-dose radiation from natural sources contributes …
[HTML][HTML] Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression
MA Grotzer, A Eggert, TJ Zuzak, AJ Janss, S Marwaha… - Oncogene, 2000 - nature.com
TNF-related apoptosis-inducing ligand (TRAIL) is a potent inducer of apoptosis in adult
malignant glioma and various other human solid tumor models but not in normal tissues. To …
malignant glioma and various other human solid tumor models but not in normal tissues. To …
MYC Messenger RNA Expression Predicts Survival Outcome in Childhood Primitive Neuroectodermal Tumor/Medulloblastoma
MA Grotzer, MD Hogarty, AJ Janss, X Liu, H Zhao… - Clinical cancer …, 2001 - AACR
Purpose and Experimental Design: Cerebellar primitive neuroectodermal tumors/medulloblastomas
(PNET/MB) are the most common malignant brain tumors in childhood. To identify …
(PNET/MB) are the most common malignant brain tumors in childhood. To identify …
Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas
Background Pediatric diffuse midline gliomas (DMGs) are incurable childhood cancers. The
imipridone ONC201 has shown early clinical efficacy in a subset of DMGs. However, the …
imipridone ONC201 has shown early clinical efficacy in a subset of DMGs. However, the …