[HTML][HTML] EMT and tumor metastasis

S Heerboth, G Housman, M Leary, M Longacre… - Clinical and translational …, 2015 - Springer
EMT and MET comprise the processes by which cells transit between epithelial and mesenchymal
states, and they play integral roles in both normal development and cancer metastasis…

Use of epigenetic drugs in disease: an overview

…, K Lapinska, N Snyder, M Leary… - Genetics & …, 2014 - journals.sagepub.com
Epigenetic changes such as DNA methylation and histone methylation and acetylation alter
gene expression at the level of transcription by upregulating, downregulating, or silencing …

Genetic and epigenetic aspects of breast cancer progression and therapy

S Byler, S Goldgar, S Heerboth, M Leary… - Anticancer …, 2014 - ar.iiarjournals.org
Although breast cancer is a heterogeneous disease that is challenging to characterize and
treat, the recent explosion of genetic and epigenetic research may help improve these …

[HTML][HTML] Sensitization of drug resistant cancer cells: a matter of combination therapy

M Leary, S Heerboth, K Lapinska, S Sarkar - Cancers, 2018 - mdpi.com
Cancer drug resistance is an enormous problem. It is responsible for most relapses in
cancer patients following apparent remission after successful therapy. Understanding cancer …

The evolution of epigenetics: from prokaryotes to humans and its biological consequences

A Willbanks, M Leary, M Greenshields… - Genetics & …, 2016 - journals.sagepub.com
The evolution process includes genetic alterations that started with prokaryotes and now
continues in humans. A distinct difference between prokaryotic chromosomes and eukaryotic …

[HTML][HTML] A comparative analysis of genetic and epigenetic events of breast and ovarian cancer related to tumorigenesis

M Longacre, NA Snyder, G Housman, M Leary… - International journal of …, 2016 - mdpi.com
Breast cancer persists as the most common cause of cancer death in women worldwide.
Ovarian cancer is also a significant source of morbidity and mortality, as the fifth leading cause …

Effects of Deltamethrin on crayfish motor axon activity and neuromuscular transmission

L Meng, PFNR Meyer, ML Leary, YF Mohammed… - Neuroscience …, 2016 - Elsevier
Deltamethrin (DM) is a widely used pesticide known to target sodium channels. Although this
compound has been studied extensively at molecular and behavioral levels, the detailed …

[HTML][HTML] Aligning implementation science with improvement practice: a call to action

…, A Brenner, A Dwyer, LK Ko, MC O'Leary… - Implementation science …, 2021 - Springer
Background In several recent articles, authors have called for aligning the fields of implementation
and improvement science. In this paper, we call for implementation science to also …

Racial/Ethnic Disparities in BRCA Counseling and Testing: a Narrative Review

CD Williams, AJ Bullard, M O'Leary, R Thomas… - Journal of racial and …, 2019 - Springer
Background/objective Despite increases in BRCA mutation testing, racial/ethnic disparities
in counseling and testing have persisted for decades. The purpose of the review was to …

[BOOK][B] Histone deacetylases

S Sarkar - 2016 - Springer
The concept of epigenetics has shifted since it was first described in the 1970s, when gene
function and expression could not always be correlated with changes in DNA sequences. …