Advances in the treatment of metastatic melanoma have improved responses and survival.
However, many patients continue to experience resistance or toxicity to treatment, …

Importance Cytotoxic CD8 + tumor-infiltrating lymphocytes (TILs) participate in immune control
of epithelial ovarian cancer; however, little is known about prognostic patterns of CD8 + …

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic
silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this …

Edmonston vaccine strains of measles virus (MV) have significant antitumor activity in
mouse xenograft models of ovarian cancer. MV engineered to express the sodium iodide …

Ligation of programmed cell death-1 (PD-1) in the tumor microenvironment is known to
inhibit effective adaptive antitumor immunity. Blockade of PD-1 in humans has resulted in …

We present an extensive quantum Monte Carlo study of the Néel to valence-bond solid (VBS)
phase transition on rectangular-and honeycomb-lattice SU (N) antiferromagnets in sign-…

Uveal melanoma is a rare type of melanoma, with only five to seven cases per one million
persons diagnosed each year. Patients with metastatic melanoma of uveal origin tend to have …

In ovarian cancer (OC), IL-17-producing T cells (Th17s) predict improved survival, whereas
regulatory T cells predict poorer survival. We previously developed a vaccine whereby patient…

Ovarian cancer remains the leading cause of death in women with gynecologic malignancies,
despite surgical advances and the development of more effective chemotherapeutics. As …

Purpose: LV305 is a modified, third-generation, nonreplicating, integration-deficient
lentivirus-based vector designed to selectively transduce dendritic cells in vivo. LV305 induces …