Identification of nesfatin-1 as a satiety molecule in the hypothalamus

…, T Monden, K Horiguchi, M Yamada, M Mori - Nature, 2006 - nature.com
The brain hypothalamus contains certain secreted molecules that are important in
regulating feeding behaviour 1 , 2 , 3 . Here we show that nesfatin, corresponding to NEFA/…

Development and evaluation of FSSG: frequency scale for the symptoms of GERD

…, T Sugiyama, M Toki, T Ohwada, M Mori - Journal of …, 2004 - Springer
Background The aim of this study was to produce a simplified questionnaire for evaluation of
the symptoms of gastroesophageal reflux disease (GERD). Methods A total of 124 patients …

[PDF][PDF] Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway

…, K Dezaki, K Hashimoto, H Shimizu, M Nakata, M Mori… - Cell metabolism, 2009 - cell.com
The hypothalamic paraventricular nucleus (PVN) functions as a center to integrate various
neuronal activities for regulating feeding behavior. Nesfatin-1, a recently discovered anorectic …

Nesfatin-1 neurons in paraventricular and supraoptic nuclei of the rat hypothalamus coexpress oxytocin and vasopressin and are activated by refeeding

…, N Yoshida, K Dezaki, T Onaka, M Mori… - …, 2008 - academic.oup.com
Nesfatin-1, a newly discovered satiety molecule, is located in the hypothalamic nuclei,
including the paraventricular nucleus (PVN) and supraoptic nucleus (SON). In this study, fine …

Thrombocytopenia associated with hepatitis C viral infection

…, T Ohtuka, K Takehara, T Arai, H Takagi, M Mori - Journal of …, 1996 - Elsevier
Background/Aims: We investigated whether chronic hepatitis C infection is associated with
thrombocytopenia. Methods/Results: Thrombocytopenia (<15×10 4 platelets/μl) was …

Expression of leptin receptor in lung: leptin as a growth factor

T Tsuchiya, H Shimizu, T Horie, M Mori - European journal of pharmacology, 1999 - Elsevier
Leptin receptors are expressed in various tissues in rodents but their function is not clear. The
present studies were undertaken to investigate the function of the leptin receptor in mouse …

Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia

…, K Yoshinari, T Machida, H Takagi, M Mori… - Biochemical and …, 2002 - Elsevier
The UDP-glucuronosyltransferase UGT1A1 plays a critical role in the detoxification of potentially
neurotoxic bilirubin by conjugating it with glucuronic acid. We identified a polymorphism …

Tertiary hypothyroidism and hyperglycemia in mice with targeted disruption of the thyrotropin-releasing hormone gene

…, K Wakabayashi, MM Taketo, M Mori - Proceedings of the …, 1997 - National Acad Sciences
Thyrotropin-releasing hormone (TRH) is a brain hypothalamic hormone that regulates thyrotropin
(TSH) secretion from the anterior pituitary and is ubiquitously distributed throughout the …

Long-term effect of eicosapentaenoic acid ethyl (EPA-E) on albuminuria of non-insulin dependent diabetic patients

H Shimizu, K Ohtani, Y Tanaka, N Sato, M Mori… - Diabetes research and …, 1995 - Elsevier
Dietary cod-liver oil containing eicosapentaenoic acid is effective on microvascular albumin
leakage in diabetic patients with albuminuria. We determined the long-term effects of oral …

Fasting concentrations of nesfatin‐1 are negatively correlated with body mass index in non‐obese males

…, K Hashimoto, T Satoh, M Kojima, M Mori - Clinical …, 2010 - Wiley Online Library
Background We recently identified a novel anorexigenic protein, nesfatin‐1, which is processed
from nesfatin/nucleobindin‐2 (NUCB2). However, the clinical importance of this protein …