The AT-rich interacting domain‑containing protein 1A gene (ARID1A) encodes ARID1A, a
member of the SWI/SNF chromatin remodeling complex. Mutation of ARID1A induces changes …

Background/Purpose: Congenital absence of the portal vein (CAPV) is a subtype of congenital
portosystemic shunt, which can cause a broad spectrum of clinical manifestations. The …

Prostasin is a serine protease present in mammalian urine that increases the activity of the
epithelial sodium channel (ENaC) when the two are coexpressed in Xenopus oocytes. To …

Lynch syndrome is a hereditary ovarian cancer with a prevalence of 0.9‑2.7%. Lynch syndrome
accounts for 10‑15% of hereditary ovarian cancers, while hereditary breast and ovarian …

Intravenous iron administration induces oxidation of serum albumin in hemodialysis patients.
Background Intravenous iron administration (IVIR) is effective for correcting anemia in …

Ovarian cancer has a poor prognosis because early detection is difficult and recurrent ovarian
cancer is usually drug-resistant. The morbidity and mortality of ovarian cancer are high …

Background: The epithelial sodium channel (ENaC) plays an important role in the regulation
of blood pressure by modulating Na reabsorption in the kidney. Dahl salt-sensitive rats on …

Liddle’s syndrome is an autosomal dominant form of salt-sensitive hypertension and has
been shown to be caused by missense or frameshift mutations in the amiloride-sensitive …

A 59-year-old woman with a 10-year history of hemodialysis was admitted to our hospital for
painful skin ulcers on her right thigh, right calf, and left upper arm. A whole-body plain …

Abstract. Prostasin, a novel serine protease, was purified from seminal fluid, and its cDNA
sequence was determined. Expression of prostasin was detected in human tissues, including …