64Cu-DOTA-trastuzumab PET imaging in patients with HER2-positive breast cancer

…, J Suzuki, Y Kono, N Honda, M Kodaira… - Journal of Nuclear …, 2013 - Soc Nuclear Med
The purpose of this study was to determine the safety, distribution, internal dosimetry, and
initial human epidermal growth factor receptor 2 (HER2)–positive tumor images of 64 Cu-…

[HTML][HTML] Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities

A Yoshida, E Kobayashi, T Kubo, M Kodaira, T Motoi… - Modern Pathology, 2017 - Elsevier
A growing number of studies suggest critical tumor suppressor roles of the SWI/SNF chromatin
remodeling complex in a variety of human cancers. The recent discovery of SMARCA4-…

CIC-rearranged sarcomas: a study of 20 cases and comparisons with Ewing sarcomas

A Yoshida, K Goto, M Kodaira… - The American journal …, 2016 - journals.lww.com
The CIC gene rearrangement exists in a subset of small round cell sarcomas. As the nosologic
relationship of these sarcomas to Ewing sarcomas remains undetermined, we examined …

[HTML][HTML] Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1

…, Y Yamamoto, K Minoura, M Ono, M Kodaira… - Nature …, 2015 - nature.com
Cancer stem cells (CSCs) have been identified in various types of cancer; however, the
mechanisms by which cells acquire CSC properties such as drug resistance and tumour seeding …

[HTML][HTML] Tumour-infiltrating lymphocytes are correlated with higher expression levels of PD-1 and PD-L1 in early breast cancer

…, E Noguchi, A Shimomura, T Shimoi, M Kodaira… - ESMO open, 2017 - Elsevier
Background The presence of tumour-infiltrating lymphocytes (TILs) is a favourable prognostic
factor in patients with early breast cancer. Programmed cell death-1 (PD-1) and its ligand …

Efficacy of everolimus, a novel m TOR inhibitor, against basal‐like triple‐negative breast cancer cells

…, Y Katanasaka, N Okamoto, M Kodaira… - Cancer …, 2012 - Wiley Online Library
Patients with triple‐negative breast cancers ( TNBC s) typically have a poor prognosis
because such cancers have no effective therapeutic targets, such as estrogen receptors for …

Phase I study of palbociclib, a cyclin‐dependent kinase 4/6 inhibitor, in Japanese patients

…, H Mukai, Y Naito, K Yonemori, M Kodaira… - Cancer …, 2016 - Wiley Online Library
This phase I study in Japanese patients evaluated the safety, pharmacokinetics, and preliminary
efficacy of palbociclib, a highly selective and reversible oral cyclin‐dependent kinase 4/…

[HTML][HTML] 64Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients

…, H Tani, Y Miyakita, Y Kanayama, Y Wada, M Kodaira… - EJNMMI research, 2015 - Springer
Background The purpose of this study was to determine whether brain metastases from
HER2-positive breast cancer could be detected noninvasively using positron emission …

Tumors with AKT1E17K Mutations Are Rational Targets for Single Agent or Combination Therapy with AKT Inhibitors

…, CM D'Cruz, M Zinda, J Lindemann, M Kodaira… - Molecular cancer …, 2015 - AACR
AKT1 E17K mutations occur at low frequency in a variety of solid tumors, including those of
the breast and urinary bladder. Although this mutation has been shown to transform rodent …

Prospective evaluation of incidence and severity of oral mucositis induced by conventional chemotherapy in solid tumors and malignant lymphomas

N Nishimura, K Nakano, K Ueda, M Kodaira… - Supportive care in …, 2012 - Springer
Purpose Oral mucositis (OM), a complication frequently associated with cancer chemotherapy,
may decrease treatment efficacy due to dose reduction or impair the patient's quality of life…