Objective Hyaluronidases (HYAL1 and HYAL2) are key enzymes in the degradation of
hyaluronan, and their expression has been altered in various cancer types. We previously …

Background The concept of the use of MRI for image-guided adaptive brachytherapy (IGABT)
in locally advanced cervical cancer was introduced 20 years ago. Here, we report on …

Several malignant tumors accumulate hyaluronan, a matrix component suggested to
promote cancer cell migration and growth. To explore the potential clinical importance of this …

BACKGROUND: Women with endometriosis often need IVF to conceive—most women
need several cycles of treatment. METHODS: To evaluate the impact of moderate to severe …

Background Platinum-based chemotherapy is the foundation of treatment for platinum-sensitive
recurrent ovarian cancer, but has substantial toxicity. Bevacizumab and maintenance …

Purpose: The purpose of this study was to investigate the expression and prognostic
significance of CD44 in epithelial ovarian cancer. Experimental Design: We analyzed the …

Versican, a proteoglycan previously reported to increase in other malignant tumours, was
studied immunohistochemically in 299 primary epithelial ovarian cancers, their 43 metastases …

Purpose This study analyzed functioning and symptom scores for longitudinal quality of life (QoL)
from patients with locally advanced cervical cancer who underwent definitive …

Placental abruption complicates about 1% of all singleton pregnancies and the aim of this
study is to assess the reproductive maternal risk factors associated with placental abruption, …

The concentration and histological distribution of hyaluronan, a tumor promoting extracellular
matrix polysaccharide, and the activity of hyaluronidase, a potential source of angiogenic …