[PDF][PDF] Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species

…, GHL Low, TJK Chung, DKH Chan, KK Tan, TLK Hon… - Immunity, 2016 - cell.com
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic
potential. Multiple DC subsets have been described, and it remains challenging to align them …

[PDF][PDF] Genomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes

…, W Gong, Z Hong, M Li, J Zhao, T Peng, Y Lu, KHT Lim… - Cancer cell, 2019 - cell.com
We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and
intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate, combined, and …

[HTML][HTML] Multidisciplinary perspective of hepatocellular carcinoma: A Pacific Northwest experience

…, C Cuevas, WP Harris, TLK Hon… - World journal of …, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most rapidly increasing type of cancer in the United
States. HCC is a highly malignant cancer, accounting for at least 14000 deaths in the United …

[HTML][HTML] Targeting glycolysis in macrophages confers protection against pancreatic ductal adenocarcinoma

…, JA Kenkel, A Pang, D Lim, HC Toh, TLK Hon… - International journal of …, 2021 - mdpi.com
Inflammation in the tumor microenvironment has been shown to promote disease
progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage …

Post-operative aspirin use and colorectal cancer-specific survival in patients with stage I-III colorectal cancer

…, WQ Leong, MH Chew, YS Pan, LKH Tony… - Anticancer …, 2014 - ar.iiarjournals.org
Background: Recent observational studies suggest that postoperative aspirin use may
improve Colorectal cancer (CRC)-specific survival and overall survival (OS). In this study, we …

Comparison between UMAP and t-SNE for multiplex-immunofluorescence derived single-cell data from tissue sections

…, GT Su-En, M Chevrier, JL Jie Hua, TL Kiat Hon… - BioRxiv, 2019 - biorxiv.org
Using human hepatocellular carcinoma (HCC) tissue samples stained with seven immune
markers including one nuclear counterstain, we compared and evaluated the use of a new …

Recommended testing algorithms for NTRK gene fusions in pediatric and selected adult cancers: Consensus of a Singapore Task Force

KHT Lim, HL Kong, KTE Chang… - Asia‐Pacific Journal …, 2022 - Wiley Online Library
The occurrence of neurotrophic tyrosine receptor kinase (NTRK) gene fusions in a wide range
of tumor types presents an attractive opportunity for using a tropomyosin receptor kinase (…

Post COVID-19 Large Vessel Vasculopathy in a Previously Healthy Young Male

…, DCB Lye, L Wang, CW Tan, KHT Lim… - … in Thrombosis and …, 2023 - thieme-connect.com
To the Editor: The rising incidence of thrombosis post-coronavirus disease 2019 (COVID-19)
1, 2 places an increased burden on health care systems, as even young patients with prior …

Overview of multiplex immunohistochemistry/immunofluorescence techniques in the era of cancer immunotherapy

…, YTF Wee, JCT Lim, J Yeong, TKH Lim - Cancer …, 2020 - Wiley Online Library
Conventional immunohistochemistry (IHC) is a widely used diagnostic technique in tissue
pathology. However, this technique is associated with a number of limitations, including high …

Inflammatory myofibroblastic tumour of the rectum with a novel anaplastic lymphoma kinase fusion diagnosed on cytology: Not just another submucosal …

M Logaswari, KHT Lim, D Tan, CAJ Ong… - …, 2022 - Wiley Online Library
Inflammatory myofibroblastic tumours (IMT) are spindle cell neoplasms most commonly
seen in the lungs, with a wide variety of less common extrapulmonary sites including the …