[HTML][HTML] Differential macrophage activation alters the expression profile of NTPDase and ecto-5′-nucleotidase
RF Zanin, E Braganhol, LS Bergamin, LFI Campesato… - PLoS …, 2012 - journals.plos.org
Macrophages are key elements in the inflammatory process, whereas depending on the
micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-…
micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-…
Alpha-bisabolol promotes glioma cell death by modulating the adenosinergic system
FB Mendes, LS Bergamin, CDS Stuepp… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Glioblastoma multiforme is the most malignant type of glioma. Alpha-bisabolol
is an essential oil reported as a potent cell death agent. In the present work, we …
is an essential oil reported as a potent cell death agent. In the present work, we …
Involvement of purinergic system in the release of cytokines by macrophages exposed to glioma‐conditioned medium
LS Bergamin, E Braganhol, F Figueiró… - Journal of cellular …, 2015 - Wiley Online Library
Macrophages are involved in cancer progression. M1 macrophages have an antitumor effect,
whereas M2 phenotype are associated with tumor growth. The progression of gliomas …
whereas M2 phenotype are associated with tumor growth. The progression of gliomas …
Pathological concentrations of homocysteine increases IL-1β production in macrophages in a P2X7, NF-ĸB, and erk-dependent manner
RF Zanin, LS Bergamin, FB Morrone… - Purinergic …, 2015 - Springer
Elevated plasma levels of homocysteine (Hcy) are associated with the development of
coronary artery disease (CAD), peripheral vascular disease, and atherosclerosis. …
coronary artery disease (CAD), peripheral vascular disease, and atherosclerosis. …
[HTML][HTML] Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth
LS Bergamin, M Capece, E Salaro, AC Sarti… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Human glioblastoma cells are strikingly refractory to ATP-stimulated, P2X7 receptor (P2X7R)-mediated
cytotoxicity. To elucidate the mechanistic basis of this feature, we investigated …
cytotoxicity. To elucidate the mechanistic basis of this feature, we investigated …
[HTML][HTML] Ectonucleotidases in tumor cells and tumor-associated immune cells: an overview
LS Bergamin, E Braganhol, RF Zanin… - BioMed Research …, 2012 - hindawi.com
Increasing evidence points out that genetic alteration does not guarantee the development
of a tumor and indicates that complex interactions of tumor cells with the microenvironment …
of a tumor and indicates that complex interactions of tumor cells with the microenvironment …
[HTML][HTML] Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line
…, L Rockenbach, F Figueiró, LS Bergamin… - Food and Chemical …, 2014 - Elsevier
Bladder cancer is the second most prevalent malignancy in the genitourinary tract and remains
a therapeutic challenge. In the search for new treatments, researchers have attempted to …
a therapeutic challenge. In the search for new treatments, researchers have attempted to …
[HTML][HTML] MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells
L Penolazzi, E Lambertini, LS Bergamin… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
The aim of this study was to investigate the role of an antichondrogenic factor, MIR221 (miR-221),
in intervertebral disc degeneration (IDD), and provide basic information for the …
in intervertebral disc degeneration (IDD), and provide basic information for the …
[HTML][HTML] Extracellular matrix from decellularized wharton's jelly improves the behavior of cells from degenerated intervertebral disc
L Penolazzi, M Pozzobon, LS Bergamin… - … in bioengineering and …, 2020 - frontiersin.org
Regenerative therapies for intervertebral disc (IVD) injuries are currently a major challenge
that is addressed in different ways by scientists working in this field. Extracellular matrix (ECM…
that is addressed in different ways by scientists working in this field. Extracellular matrix (ECM…
[HTML][HTML] Hypoxia preconditioning of human MSCs: a direct evidence of HIF-1α and collagen type XV correlation
…, L Penolazzi, M Angelozzi, LS Bergamin… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mesenchymal stromal cells (MSCs) hold considerable promise in bone
tissue engineering, but their poor survival and potency when in vivo implanted limits their …
tissue engineering, but their poor survival and potency when in vivo implanted limits their …