[HTML][HTML] Differential macrophage activation alters the expression profile of NTPDase and ecto-5′-nucleotidase

RF Zanin, E Braganhol, LS Bergamin, LFI Campesato… - PLoS …, 2012 - journals.plos.org
Macrophages are key elements in the inflammatory process, whereas depending on the
micro-environmental stimulation they exhibit a pro-inflammatory (classical/M1) or an anti-…

Alpha-bisabolol promotes glioma cell death by modulating the adenosinergic system

FB Mendes, LS Bergamin, CDS Stuepp… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Glioblastoma multiforme is the most malignant type of glioma. Alpha-bisabolol
is an essential oil reported as a potent cell death agent. In the present work, we …

Involvement of purinergic system in the release of cytokines by macrophages exposed to glioma‐conditioned medium

LS Bergamin, E Braganhol, F Figueiró… - Journal of cellular …, 2015 - Wiley Online Library
Macrophages are involved in cancer progression. M1 macrophages have an antitumor effect,
whereas M2 phenotype are associated with tumor growth. The progression of gliomas …

Pathological concentrations of homocysteine increases IL-1β production in macrophages in a P2X7, NF-ĸB, and erk-dependent manner

RF Zanin, LS Bergamin, FB Morrone… - Purinergic …, 2015 - Springer
Elevated plasma levels of homocysteine (Hcy) are associated with the development of
coronary artery disease (CAD), peripheral vascular disease, and atherosclerosis. …

[HTML][HTML] Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth

LS Bergamin, M Capece, E Salaro, AC Sarti… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Human glioblastoma cells are strikingly refractory to ATP-stimulated, P2X7 receptor (P2X7R)-mediated
cytotoxicity. To elucidate the mechanistic basis of this feature, we investigated …

[HTML][HTML] Ectonucleotidases in tumor cells and tumor-associated immune cells: an overview

LS Bergamin, E Braganhol, RF Zanin… - BioMed Research …, 2012 - hindawi.com
Increasing evidence points out that genetic alteration does not guarantee the development
of a tumor and indicates that complex interactions of tumor cells with the microenvironment …

[HTML][HTML] Quinovic acid glycosides purified fraction from Uncaria tomentosa induces cell death by apoptosis in the T24 human bladder cancer cell line

…, L Rockenbach, F Figueiró, LS Bergamin… - Food and Chemical …, 2014 - Elsevier
Bladder cancer is the second most prevalent malignancy in the genitourinary tract and remains
a therapeutic challenge. In the search for new treatments, researchers have attempted to …

[HTML][HTML] MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells

L Penolazzi, E Lambertini, LS Bergamin… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
The aim of this study was to investigate the role of an antichondrogenic factor, MIR221 (miR-221),
in intervertebral disc degeneration (IDD), and provide basic information for the …

[HTML][HTML] Extracellular matrix from decellularized wharton's jelly improves the behavior of cells from degenerated intervertebral disc

L Penolazzi, M Pozzobon, LS Bergamin… - … in bioengineering and …, 2020 - frontiersin.org
Regenerative therapies for intervertebral disc (IVD) injuries are currently a major challenge
that is addressed in different ways by scientists working in this field. Extracellular matrix (ECM…

[HTML][HTML] Hypoxia preconditioning of human MSCs: a direct evidence of HIF-1α and collagen type XV correlation

…, L Penolazzi, M Angelozzi, LS Bergamin… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mesenchymal stromal cells (MSCs) hold considerable promise in bone
tissue engineering, but their poor survival and potency when in vivo implanted limits their …